ArticleScientific reports2022
The prevalence and natural history of hepatic cysts examined by ultrasound: a health checkup population retrospective cohort study.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Healthcare burden and clinical spectrum of symptomatic polycystic liver disease in Japan: a nationwide epidemiological survey.Journal of gastroenterology · 2026Article
- Frequency, Plausibility and Internal Consistency of International Classification of Diseases (ICD) Coding Related to Cystic Echinococcosis Within the Jordanian Ministry of Health Database: A Quality-Assurance Study.Healthcare (Basel, Switzerland) · 2026Article
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- Suturing liver's round ligament to cystic wall for hepatic cysts.World journal of gastrointestinal surgery · 2025Article
- Observational
- Imaging insights into pediatric liver masses: A comprehensive minireview for hepatology practice.World journal of hepatology · 2025Review
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- Giant complex hepatic cyst causing pseudocystitis: A case report.World journal of clinical cases · 2023Article
- Endoscopic observation of a lumen of a large hepatic cyst with aspiration and ethanol sclerotherapy: Case report and literature review.International journal of surgery case reports · 2023Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
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Abstract
The prevalence of hepatic cysts in the general population and their natural history are largely unknown. This study aimed to assess the prevalence and natural history of hepatic cysts by investigating health checkup participants. Ultrasonographic data of health checkup participants (n = 38,842) were retrospectively evaluated to calculate its prevalence. In addition, we assessed the changes in the size and characteristics of hepatic cysts over 10 years (n = 7709). We found the prevalence of hepatic cysts was 21.9%. Older age, female sex, and presence of kidney cysts or pancreatic cysts were associated with the occurrence of hepatic cysts. Younger age, female sex, and the existence of multiple hepatic cysts were associated with cyst enlargement. Among 126 individuals who had hepatic cysts with a diameter of 30 mm or larger at the first visit, two (1.6%) required treatment. Remain 124 cases showed four patterns: 44 cases with enlargement, 47 stable, 11 regression after enlargement, and 22 regression. Hyperechoic fluid inside the cysts was observed in 54.5% (18 of 33), which was significantly higher than 6.6% (6 of 91) of the non-regression (OR = 17.0). The appearance of intracystic hyperechoic fluid by ultrasound may predict subsequent regression of the hepatic cyst.
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