Observational studyBMJ open2022
Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort study.
Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
17 citing papers in PubMed.
- Secondary fragility fractures after hip fracture surgery in four thousand, four hundred and eighteen older adults: risk factors and internal validation of an interpretable machine-learning model.International orthopaedics · 2026Article
- Position paper: a coordinated approach to fracture and fall prevention from seven international organizations.European geriatric medicine · 2026Article
- Effects of romosozumab on the peripheral and axial skeleton in postmenopausal women at high fracture risk: real-world evidence from DXA and HR-pQCT data.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Predictors for falling within six months after surgery in patients with hemiarthroplasty after an acute femoral neck fracture.Scientific reports · 2026Article
- Advancing fracture risk prediction: established assessment tools and emerging HR-pQCT-based approaches.Frontiers in endocrinology · 2026Review
- The global burden of fractures and its underlying etiologies: results from and further analysis of the Global Burden of Disease Study 2021.Archives of osteoporosis · 2025Article
- Immediate risk factors for fracture recurrence after initial fractures, based on fracture liaison service dataset, and comparison with fall risk factors reported in the literature.European geriatric medicine · 2025Article
- Systematic evaluation of abdominal aortic calcification in patients with a recent clinical fracture visiting the Fracture Liaison Service.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Correlation between facial bone fractures and associated long bone injuries in polytrauma patients: A retrospective imaging-based study.Bioinformation · 2025Article
- The Fracture Phenotypes in Women and Men of 50 Years and Older with a Recent Clinical Fracture.Current osteoporosis reports · 2024Review
- Secondary fracture prevention in primary care: a narrative review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Review
- Physical performance and sarcopenia assessment in patients with a recent fracture visiting the Fracture Liaison Service.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
- The Dutch multidisciplinary guideline osteoporosis and fracture prevention, taking a local guideline to the international arena.Archives of osteoporosis · 2024Article
- The "Can Do, Do Do" Framework Applied to Assess the Association between Physical Capacity, Physical Activity and Prospective Falls, Subsequent Fractures, and Mortality in Patients Visiting the Fracture Liaison Service.Journal of personalized medicine · 2024Article
- Characterizing Bone Phenotypes Related to Skeletal Fragility Using Advanced Medical Imaging.Current osteoporosis reports · 2023Review
- Targeted optimum care approach for osteoporotic fragility fractures: tailored strategy based on risk stratification to reduce incidents of falls-an initiative by the Egyptian Academy of bone health based on the FLS national register.Archives of osteoporosis · 2023Observational
- Physical Functioning in Patients with a Recent Fracture: The "Can Do, Do Do" Framework Applied to Explore Physical Capacity, Physical Activity and Fall Risk Factors.Calcified tissue international · 2023Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the risk of subsequent fractures in patients who attended the Fracture Liaison Service (FLS), with and without incident falls after the index fracture.
designA 3-year prospective observational cohort study.
settingAn outpatient FLS in the Netherlands.
participantsPatients aged 50+ years with a recent clinical fracture. OUTCOME MEASURES: Incident falls and subsequent fractures.
resultsThe study included 488 patients (71.9% women, mean age: 64.6±8.6 years). During the 3-year follow-up, 959 falls had been ascertained in 296 patients (60.7%) (ie, fallers), and 60 subsequent fractures were ascertained in 53 patients (10.9%). Of the fractures, 47 (78.3%) were fall related, of which 25 (53.2%) were sustained at the first fall incident at a median of 34 weeks. An incident fall was associated with an approximately 9-fold (HR: 8.6, 95% CI 3.1 to 23.8) increase in the risk of subsequent fractures.
conclusionThese data suggest that subsequent fractures among patients on treatment prescribed in an FLS setting are common, and that an incident fall is a strong predictor of subsequent fracture risk. Immediate attention for fall risk could be beneficial in an FLS model of care. TRIAL REGISTRATION NUMBER: NL45707.072.13.
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