Evidence map›Paper›PMID 35896175›Full record

ArticleClinical chemistry2022

Macrotroponin Complex as a Cause for Cardiac Troponin Increase after COVID-19 Vaccination and Infection.

Anda Bularga, Ellen Oskoui, Takeshi Fujisawa, Sara Jenks, Rachel Sutherland, Fred S Apple, Ola Hammarsten, Nicholas L Mills

Erratum issuedAbstract read
In one paragraph

Article in Clinical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Handling persistent cardiac troponin elevation in asymptomatic athletes: The role of macrocomplexes.American heart journal plus : cardiology research and practice · 2026
    Article
  3. Cardiac troponin T elevation predicts mortality in hospitalized COVID-19 patients.American heart journal plus : cardiology research and practice · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Anda BulargaBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-5530-527X
Ellen OskouiBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Takeshi FujisawaBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Sara JenksDepartment Clinical Biochemistry, Royal Infirmary of Edinburgh, Edinburgh, UK.
Rachel SutherlandDepartment of Acute Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.
Fred S AppleDepartments of Laboratory Medicine and Pathology, Hennepin Healthcare/Hennepin County Medical Center and University of Minnesota, Minneapolis, MN, USA.
Ola HammarstenDepartment of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Nicholas L MillsBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-0533-7991

Funding

British Heart Foundation CH/F/21/90010British Heart Foundation RE/18/5/34216British Heart Foundation RG/20/10/34966Medical Research Council MR/V007254/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19COVID-19 VaccinesHumansTroponin IVaccinationCOVID-19 VaccinesTroponin ICOVID-19High-sensitivity cardiac troponinmRNA SARS-CoV-2 vaccine

Identifiers

PMID35896175
PMCPMC9384580

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.