Evidence map›Paper›PMID 35896138›Full record

ArticleJournal of affective disorders2022

Adverse childhood experiences and adolescent mental health: Understanding the roles of gender and teenage risk and protective factors.

Jamie M Gajos, Chelsea R Miller, Lindsay Leban, Karen L Cropsey

Abstract read
In one paragraph

Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Early Exposure to a Parent's Alcohol Use Disorder as an Adverse Childhood Experience: Neurobiological and Clinical Consequences in Adulthood.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  3. Social emotional learning and autonomic regulation enhance social connectedness in female adolescents with extensive exposure to adverse childhood experiences.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jamie M GajosDepartment of Human Development and Family Studies, The University of Alabama, Tuscaloosa, AL, United States. Electronic address: jmgajos@ua.edu.
Chelsea R MillerDepartment of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Lindsay LebanDepartment of Criminal Justice, University of Alabama at Birmingham, Birmingham, AL, United States.
Karen L CropseyDepartment of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States.

Funding

Fragile Families and the Transition to AdulthoodR01HD036916 · NICHD · PRINCETON UNIVERSITY · PI Kathryn Edin, Jane Waldfogel · 1999 to 2026
$46.3M
ECONOMIC STATUS, PUBLIC POLICY, AND CHILD NEGLECTR01HD039135 · NICHD · PRINCETON UNIVERSITY · PI PAXSON, CHRISTINA H · 2000 to 2004
$3.1M
Child Care and Parental Employment in Fragile FamiliesR01HD040421 · NICHD · COLUMBIA UNIVERSITY TEACHERS COLLEGE · PI BROOKS-GUNN, JEANNE · 2002 to 2006
$2.8M
Momentary Geospatial, Psychological, and Behavioral Risk for Substance Use in Young Adults Under Criminal Justice SupervisionK01DA054262 · NIDA · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI Jamie Gajos · 2022 to 2026
$855k
NICHD NIH HHS R01 HD036916NICHD NIH HHS R01 HD039135NICHD NIH HHS R01 HD040421NIDA NIH HHS K01 DA054262
6 · The paper itself

Abstract

Adverse Childhood Experiences (ACEs) have been linked to a host of negative outcomes in adolescence. However, research on the impact of ACEs on adolescent mental health has produced mixed results, leaving it unclear how ACEs may relate to depression and anxiety during adolescence. Moreover, this body of work has neglected how gender, risk and protective factors may influence these relationships, despite research demonstrating gender differences in both responses to adversity and in the impact of risk and protective factors on maladaptive outcomes in adolescence. Drawing on a sample of at-risk youth from the Fragile Families and Child Wellbeing Study (N = 2455; age 14-18; 48 % female, 50 % Black, 23 % Hispanic), the current study examines the association between ACEs during early childhood (i.e., ages 1 to 5) and anxious and depressive tendencies reported during adolescence. Models are stratified by gender and incorporate six types of teenage risk and protective factors (peer bullying, delinquent peers, low self-control, parental attachment, collective efficacy, and school connectedness). Results showed support for gender differences in the associations between ACEs and boys' and girls' mental health symptoms. Initially, ACEs were associated with an increased risk of both depressive and anxious tendencies in boys, but the total ACEs score was only significantly associated with an increased risk for depressive symptoms in girls. After accounting for teenage protective factors, ACEs were related to a decreased risk of depressive and anxious symptoms among girls only. Findings have important implications for refining intervention and prevention strategies focusing on mitigating the harms of ACEs.

Indexed as

Adverse Childhood ExperiencesMental DisordersAdolescentAnxietyChildChild, PreschoolFemaleHumansInfantMaleMental HealthProtective FactorsAdolescent mental healthAdolescent risk and protective factorsAdverse childhood experiencesGender differences

Identifiers

PMID35896138
PMCPMC10840483

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.