Evidence map›Paper›PMID 35895821›Full record

ArticleScience advances2022

Ultrasensitive point-of-care biochemical sensor based on metal-AIEgen frameworks.

Jiangjiang Zhang, Ying Li, Fengli Chai, Qizhen Li, Dou Wang, Liping Liu, Ben Zhong Tang, Xingyu Jiang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 100 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jiangjiang ZhangGuangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering and Department of Hepatobiliary and Pancreas Surgery (The First Affiliated Hospital), Southern University of Science and Technology, No. 1088 Xueyuan Rd., Nanshan District, Shenzhen, Guangdong 518055, P. R. China.ORCID 0000-0002-9647-5101
Ying LiCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen, Guangdong 518060, P. R. China.ORCID 0000-0002-9595-6296
Fengli ChaiGuangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering and Department of Hepatobiliary and Pancreas Surgery (The First Affiliated Hospital), Southern University of Science and Technology, No. 1088 Xueyuan Rd., Nanshan District, Shenzhen, Guangdong 518055, P. R. China.ORCID 0000-0003-4220-1268
Qizhen LiGuangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering and Department of Hepatobiliary and Pancreas Surgery (The First Affiliated Hospital), Southern University of Science and Technology, No. 1088 Xueyuan Rd., Nanshan District, Shenzhen, Guangdong 518055, P. R. China.
Dou WangGuangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering and Department of Hepatobiliary and Pancreas Surgery (The First Affiliated Hospital), Southern University of Science and Technology, No. 1088 Xueyuan Rd., Nanshan District, Shenzhen, Guangdong 518055, P. R. China.
Liping LiuGuangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering and Department of Hepatobiliary and Pancreas Surgery (The First Affiliated Hospital), Southern University of Science and Technology, No. 1088 Xueyuan Rd., Nanshan District, Shenzhen, Guangdong 518055, P. R. China.ORCID 0000-0001-7017-301X
Ben Zhong TangCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen, Guangdong 518060, P. R. China.ORCID 0000-0002-0293-964X
Xingyu JiangGuangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering and Department of Hepatobiliary and Pancreas Surgery (The First Affiliated Hospital), Southern University of Science and Technology, No. 1088 Xueyuan Rd., Nanshan District, Shenzhen, Guangdong 518055, P. R. China.ORCID 0000-0002-5008-4703
Southern University of Science and Technology · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Point-of-care (POC) biochemical sensors have found broad applications in areas ranging from clinical diagnosis to environmental monitoring. However, POC sensors often suffer from poor sensitivity. Here, we synthesized a metal-organic framework, where the ligand is the aggregation-induced emission luminogen (AIEgen), which we call metal-AIEgen frameworks (MAFs), for use in the ultrasensitive POC biochemical sensors. MAFs process a unique luminescent mechanism of structural rigidity-enhanced emission to achieve a high quantum yield (~99.9%). We optimized the MAFs to show 10

Identifiers

PMID35895821
PMCPMC9328688
OpenAlexW4288050246

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.