Evidence map›Paper›PMID 35895683›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Ciliogenesis requires sphingolipid-dependent membrane and axoneme interaction.

Dou Wu, Jingying Huang, Hao Zhu, Zhe Chen, Yongping Chai, Jingyi Ke, Kexin Lei, Zhao Peng, Ranhao Zhang, Xueming Li and 4 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Ciliary Membrane Lipid Homeostasis in Health and Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Comparative Proteomics of Plasma and Flagellar Membranes inInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Review
  5. Tppp3 determines basal body positioning and identity of respiratory cilia via microtubule assembly and sphingolipid homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Article
  8. The intraflagellar transport cycle.Nature reviews. Molecular cell biology · 2025
    Review
  9. Review
  10. A mutualistic bacterium rescues a green alga from an antagonist.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Dou WuTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Jingying HuangTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Hao ZhuTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-9964-9851
Zhe ChenTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Yongping ChaiTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-9555-7239
Jingyi KeTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Kexin LeiTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Zhao PengKey Laboratory of Algal Biology, Chinese Academy of Sciences, Wuhan 430072, China.ORCID 0000-0002-5451-8468
Ranhao ZhangTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Xueming LiTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Kaiyao HuangKey Laboratory of Algal Biology, Chinese Academy of Sciences, Wuhan 430072, China.ORCID 0000-0001-8669-1065
Wei LiSchool of Medicine, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-9133-461X
Chengtian ZhaoMinistry of Education Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao, 266100, China.ORCID 0000-0003-1236-914X
Guangshuo OuTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0003-1512-7824
Chinese Institute for Brain Research · CNCenter for Life Sciences · CNChinese Academy of Sciences · CNQingdao National Laboratory for Marine Science and Technology · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cilium formation and regeneration requires new protein synthesis, but the underlying cytosolic translational reprogramming remains largely unknown. Using ribosome footprinting, we performed global translatome profiling during cilia regeneration in

Indexed as

AxonemeChlamydomonasCiliaFlagellaRegenerationSphingolipidsCeramidesProtein TransportCeramidesSphingolipidsciliacryo-electron tomographyribosome profilingsphingolipid

Identifiers

PMID35895683
PMCPMC9351462
OpenAlexW4288051858

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.