Evidence map›Paper›PMID 35895415›Full record

ArticleThe American journal of tropical medicine and hygiene2022

Genomic Sequencing of Dengue Virus Strains Associated with Papua New Guinean Outbreaks in 2016 Reveals Endemic Circulation of DENV-1 and DENV-2.

Marinjho Jonduo, Matthew J Neave, Sarah Javati, Dorothy Abala, Eric Bilo, Anthony Kini, Janlyn Kumbu, Moses Laman, Leanne J Robinson, Leo Makita and 5 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Whole Genome Sequencing of DENV-2 isolated frombioRxiv : the preprint server for biology · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marinjho JonduoPapua New Guinea Institute of Medical Research, Goroka, Eastern Highlands Province, Papua New Guinea.
Matthew J NeaveCSIRO Australian Centre for Disease Preparedness, Geelong, Victoria, Australia.
Sarah JavatiPapua New Guinea Institute of Medical Research, Goroka, Eastern Highlands Province, Papua New Guinea.
Dorothy AbalaCentral Public Health Laboratory, Port Moresby, Papua New Guinea.
Eric BiloCentral Public Health Laboratory, Port Moresby, Papua New Guinea.
Anthony KiniCentral Public Health Laboratory, Port Moresby, Papua New Guinea.
Janlyn KumbuCentral Public Health Laboratory, Port Moresby, Papua New Guinea.
Moses LamanPapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Leanne J RobinsonPapua New Guinea Institute of Medical Research, Madang, Madang Province, Papua New Guinea.
Leo MakitaPapua New Guinea National Department of Health, Port Moresby, Papua New Guinea.
Melinda SusapuPapua New Guinea National Department of Health, Port Moresby, Papua New Guinea.
William PomatPapua New Guinea Institute of Medical Research, Goroka, Eastern Highlands Province, Papua New Guinea.
Mohammad Yazid AbdadPapua New Guinea Institute of Medical Research, Goroka, Eastern Highlands Province, Papua New Guinea.
David T WilliamsCSIRO Australian Centre for Disease Preparedness, Geelong, Victoria, Australia.
Paul F HorwoodPapua New Guinea Institute of Medical Research, Goroka, Eastern Highlands Province, Papua New Guinea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decade, the Pacific region has experienced many arboviral outbreaks, including dengue, chikungunya, and Zika viruses. Papua New Guinea (PNG) has a high burden of arboviral diseases, but there is a paucity of knowledge about the epidemiology and circulation of these viruses in the country. In this study, we report investigations into suspected arboviral outbreaks of febrile disease in PNG from December 2015 to June 2017. DENV-1 and DENV-2 were the mostly commonly detected viruses, and low circulation of DENV-3 and ZIKV was also detected. DENV-4 and CHIKV were not detected during this period. Full genome sequencing of selected positive samples revealed that circulation was dominated by endemic indigenous strains belonging to DENV-1 (genotype IV) and DENV-2 (genotype C) that have been present in the country for up to a decade. A DENV-2 sublineage was also identified that has been associated with outbreaks of severe dengue in both PNG and the Solomon Islands.

Indexed as

ArbovirusesChikungunya FeverDengueDengue VirusZika VirusZika Virus InfectionDisease OutbreaksGenomicsHumansPapua New Guinea

Identifiers

PMID35895415
PMCPMC9768287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.