ArticleEuropean radiology2023
Influence of dilution on arterial-phase artifacts and signal intensity on gadoxetic acid-enhanced liver MRI.
Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- [Expert consensus on overall standardized management of gadoxetate disodium-enhanced MRI examinations (version 2026)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Article
- Reducing respiratory artifacts in gadoxetic acid-enhanced magnetic resonance imaging via a patient-adapted breath-holding training strategy.Quantitative imaging in medicine and surgery · 2026Article
- Super-delayed-phase imaging on gadoxetic acid-enhanced MRI: do we need it? Are there other alternatives for improving liver parenchymal enhancement?European radiology · 2025Article
- Super delayed phase imaging in gadoxetic acid-enhanced MRI: investigating factors contributing to improved liver contrast.European radiology · 2025Article
- Imaging cholangiocarcinoma: CT and MRI techniques.Abdominal radiology (New York) · 2025Review
- Are dilution, slow injection and care bolus technique the causal solution to mitigating arterial-phase artifacts on gadoxetic acid-enhanced MRI? A large-cohort study.European radiology · 2024Article
- Intra-patient and inter-observer image quality analysis in liver MRI study with gadoxetic acid using two different multi-arterial phase techniques.The British journal of radiology · 2024Article
- Effect of body mass index (BMI) on image contrast in the hepatobiliary phase of Gd-EOB-DTPA-enhanced-MRI and the feasibility of the application of half-dose Gd-EOB-DTPA to hepatobiliary phase imaging in patients with a BMI less than 24: a comparative study.Quantitative imaging in medicine and surgery · 2023Article
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
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Abstract
objectivesTo investigate the effect of saline-diluted gadoxetic acid, done for arterial-phase (AP) artifact reduction, on signal intensity (SI), and hence focal lesion conspicuity on MR imaging.
methodsWe retrospectively examined 112 patients who each had at least two serial gadoxetic acid-enhanced liver MRIs performed at 1 ml/s, first with non-diluted (ND), then with 1:1 saline-diluted (D) contrast. Two blinded readers independently analyzed the artifacts and graded dynamic images using a 5-point scale. The absolute SI of liver parenchyma, focal liver lesions (if present), aorta, and portal vein at the level of the celiac trunk and the SI of the paraspinal muscle were measured in all phases. The signal-to-norm (SI
resultsAP artifacts were significantly reduced with dilution. Mean absolute contrast-enhanced liver SI was significantly higher on the D exams compared to the ND exams. Likewise, SI
conclusionGadoxetic acid dilution injected at 1ml/s produces images with significantly fewer AP artifacts but no significant loss in SI KEY POINTS: • Diluted gadoxetic acid at slow injection (1 ml/s) yielded images with higher SI
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