Evidence map›Paper›PMID 35894649›Full record

ArticleACS infectious diseases2022

Random Forest Model Predictions Afford Dual-Stage Antimalarial Agents.

Haseeb Mughal, Elise C Bell, Khadija Mughal, Emily R Derbyshire, Joel S Freundlich

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Haseeb MughalDepartment of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey 07103, United States.
Elise C BellDepartment of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27708, United States.
Khadija MughalDepartment of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey 07103, United States.
Emily R DerbyshireDepartment of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27708, United States.ORCID 0000-0001-6664-8844
Joel S FreundlichDepartment of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey 07103, United States.ORCID 0000-0002-3411-3455
Rutgers, The State University of New Jersey · USDuke University · US

Funding

Therapeutics for drug resistant-bacteria: Arylpropionyl-phloroglucinolsU19AI109713 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI LU, MIN · 2014 to 2018
$26.9M
Enabling Host Processes for Defense Against Liver Stage Malaria InfectionDP2AI138239 · NIAID · DUKE UNIVERSITY · PI DERBYSHIRE, EMILY R · 2017 to 2017
$2.3M
NIAID NIH HHS DP2 AI138239NIAID NIH HHS U19 AI109713
6 · The paper itself

Abstract

The need for novel antimalarials is apparent given the continuing disease burden worldwide, despite significant drug discovery advances from the bench to the bedside. In particular, small-molecule agents with potent efficacy against both the liver and blood stages of

Indexed as

AntimalarialsMalariaMalaria, FalciparumHumansPlasmodium bergheiPlasmodium falciparumProspective StudiesAntimalarialsantimalarialdual-stagePlasmodium spp.random forest

Identifiers

PMID35894649
PMCPMC9987178
OpenAlexW4288067740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.