Evidence map›Paper›PMID 35894196›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2022

[Association of maternal

Qian Chen, Peng Huang, Xin-Li Song, Yi-Ping Liu, Meng-Ting Sun, Ting-Ting Wang, Sen-Mao Zhang, Jia-Bi Qin

Abstract read
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In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qian ChenDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Peng Huang
Xin-Li SongDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Yi-Ping LiuDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Meng-Ting SunDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Ting-Ting WangDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Sen-Mao ZhangDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Jia-Bi QinDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the association of maternal methylenetetrahydrofolate dehydrogenase 1 (

methodsA hospital-based case-control study was conducted. The mothers of 683 children with CHD alone who attended Hunan Children's Hospital, from November 2017 to March 2020 were enrolled as the case group, and the mothers of 740 healthy children who attended the same hospital during the same period and did not have any deformity were enrolled as the control group. A questionnaire survey was performed to collect related exposure data, and then venous blood samples (5 mL) were collected from the mothers to detect

resultsThe multivariate logistic regression analysis showed that maternal

conclusionsMaternal

Indexed as

AminohydrolasesHeart Defects, CongenitalMethylenetetrahydrofolate Dehydrogenase (NADP)Multifunctional EnzymesCase-Control StudiesChildFemaleGenetic Predisposition to DiseaseHumansMinor Histocompatibility AntigensMothersPolymorphism, Single NucleotideRisk FactorsAminohydrolasesMethylenetetrahydrofolate Dehydrogenase (NADP)Minor Histocompatibility AntigensMTHFD1 protein, humanMTHFD2 protein, humanMultifunctional EnzymesCase-control studyCongenital heart diseaseGene-gene interactionHaplotypeMethylenetetrahydrofolate dehydrogenaseOffspring

Identifiers

PMID35894196
PMCPMC9336623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.