Evidence map›Paper›PMID 35894146›Full record

ArticleOrthopaedic surgery2022

A Mid-term Follow-up Study on the Reimplantation of Autoclaved Femoral and Tibial Components as Spacers for Treating Infected Total Knee Arthroplasty.

Peng Li, Zhiqi Zhu, Xiangyang Tang, Zhanjun Shi

Open access · goldAbstract read
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Article in Orthopaedic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Peng LiDepartment of Orthopedic Surgery, Longgang District People's Hospital of Shenzhen & The Second Affiliated Hospital of The Chinese University of Hong Kong, Shenzhen, China.ORCID https://orcid.org/0000-0001-9432-2569
Zhiqi ZhuDepartment of Orthopedic Surgery, Longgang District People's Hospital of Shenzhen & The Second Affiliated Hospital of The Chinese University of Hong Kong, Shenzhen, China.
Xiangyang TangDepartment of Orthopedic Surgery, Longgang District People's Hospital of Shenzhen & The Second Affiliated Hospital of The Chinese University of Hong Kong, Shenzhen, China.
Zhanjun ShiDepartment of Orthopedic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Chinese University of Hong Kong, Shenzhen · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInfection after total knee arthroplasty (TKA) is a rare but devastating complication. Different types of spaces have been used in two-stage revision. The study aimed to evaluate the effect of autoclaved femoral and tibial components as spacers for treating periprosthetic infections after TKA.

methodsA retrospective study was performed for 13 patients (five males, eight females) with a mean age of 69 ± 6 (range, 57-80) years and suffering from periprosthetic infection after TKA. They were treated with unconventional two-stage revision from May 2008 to June 2017. In the first-stage surgery, the autoclaved femoral and tibial components were reimplanted with a new liner as a spacer after a thorough debridement. After 4-6 months, the second-stage surgery was performed according to the patients' requirements. The knee society score (KSS) and knee range of motion (ROM) were assessed before and after surgery. The reinfection rate was calculated.

resultsThe mean duration of follow-up was 5.7 ± 2.1 (range, 3.1-8.8) years. Culture-positive infections comprised 69% of the cohort. All patients were able to walk 24 h after the first stage surgery, and the knee ROM could reach 90° in 1 week. Two patients (15.4%) experienced an infection recurrence. One patient was reinfected 1 year after the first stage surgery. Another patient developed reinfection 3 years after surgery but did not choose re-revision and died of pneumonia. Only one patient underwent the second stage revision. The remaining 10 patients refused to receive a new prosthesis. At the time of the final follow-up, six patients had slight pain in the knee while walking, and one patient required crutches to walk. There were no signs of prosthesis dislocation, rupture, deep vein thrombosis, pulmonary embolism, or delayed wound healing. No radiolucent lines or osteolysis were found. The mean KSS improved from 51 ± 10 (range, 35-63) points preoperatively to 79 ± 5 (range, 60-85) points at the final follow-up. The average ROM before and after the first stage surgery were 62° ± 29° (range, 10°-100°) and 104° ± 9° (range, 90°-120°) (t = 4.659, P < 0.01) respectively. The infection control rate was 84.6%.

conclusionReimplantation of the autoclaved original femoral and tibial components as an articulating spacer during the first stage surgery is a valuable addition for treating an infected TKA.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisProsthesis-Related InfectionsAgedAnti-Bacterial AgentsFemaleFollow-Up StudiesHumansKnee JointMaleMiddle AgedReinfectionReoperationReplantationRetrospective StudiesTreatment OutcomeAnti-Bacterial AgentsArthroplastyComponentDisinfectionInfectionReplantationSpacer

Identifiers

PMID35894146
PMCPMC9483052
OpenAlexW4288068689

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.