Evidence map›Paper›PMID 35894025›Full record

ArticleTomography (Ann Arbor, Mich.)2022

The Diagnostic Performance of Multi-Detector Computed Tomography (MDCT) in Depiction of Acute Spondylodiscitis in an Emergency Department.

Alberto Negro, Francesco Somma, Mario Tortora, Marina Lugarà, Stefania Tamburrini, Maria Gabriella Coppola, Valeria Piscitelli, Fabrizio Fasano, Carmine Sicignano, Ottavia Vargas and 15 more

Open access · goldAbstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Vanishing vacuum disc phenomenon: A diagnostic key in spinal infection.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  2. Sex life and low back pain: The impact of intradiscal ozone therapy in patients with herniated lumbar disc.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 2 institutions in 1 country.

Alberto NegroDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.ORCID 0000-0002-7904-1563
Francesco SommaDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.ORCID 0000-0002-8193-3050
Mario TortoraDepartment of Advanced Biomedical Sciences, Federico II University Naples, 80131 Naples, Italy.ORCID 0000-0002-4745-3061
Marina LugaràDepartment of Internal Medicine, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Stefania TamburriniDepartment of Radiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.ORCID 0000-0003-0455-0256
Maria Gabriella CoppolaDepartment of Internal Medicine, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.ORCID 0000-0003-0834-7546
Valeria PiscitelliDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.ORCID 0000-0003-2315-526X
Fabrizio FasanoDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Carmine SicignanoDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Ottavia VargasDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Gianvito PaceDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Mariarosaria GiardielloDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Michele IannuzziDepartment of Anesthesia and Intensive Care, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Gabriella ToroDepartment of Radiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Fiore De SimoneDepartment of Radiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Marco CatalanoDepartment of Radiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Roberto CarboneDepartment of Radiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Concetta RoccoDepartment of Radiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Pietro Paolo SaturninoDepartment of Radiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Luigi Della GattaDepartment of Neuoradiology, AORN A. Cardarelli, Via Antonio Cardarelli, 80131 Naples, Italy.
Alessandro VillaDepartment of Neurorsurgery, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Fabio TortoraDepartment of Advanced Biomedical Sciences, Federico II University Naples, 80131 Naples, Italy.
Laura GeminiDepartment of Advanced Biomedical Sciences, Federico II University Naples, 80131 Naples, Italy.ORCID 0000-0002-0045-4673
Ferdinando CaranciDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via de Crecchio, 80138 Naples, Italy.
Vincenzo D'AgostinoDepartment of Neuroradiology, Ospedale del Mare, Via Enrico Russo, 80147 Naples, Italy.
Ospedale Antonio Cardarelli · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis of acute spondylodiscitis can be very difficult because clinical onset symptoms are highly variable. The reference examination is MRI, but very often the first diagnostic investigation performed is CT, given its high availability in the acute setting. CT allows rapid evaluation of other alternative diagnoses (e.g., fractures), but scarce literature is available to evaluate the accuracy of CT, and in particular of multi-detector computed tomography (MDCT), in the diagnosis of suspected spondylodiscitis. The aim of our study was to establish MDCT accuracy and how this diagnostic method could help doctors in the depiction of acute spondylodiscitis in an emergency situation by comparing the diagnostic performance of MDCT with MRI, which is the gold standard.

methodsWe searched our radiological archive for all MRI examinations of patients who had been studied for a suspicion of acute spondylodiscitis in the period between January 2017 and January 2021 (

resultsMDCT allowed identification of the presence of acute spondylodiscitis in 13 of 25 patients. Specificity and positive predictive value were 100% for MDCT, while sensitivity and negative predictive value were 68% and 50%, respectively, achieving an overall accuracy of 76%. In addition, MDCT allowed the identification of paravertebral abscesses (92%), fairly pathognomonic lesions of spondylodiscitis pathology.

conclusionsThe MDCT allows identification of the presence of acute spondylodiscitis in the Emergency Department (ED) with a satisfactory accuracy. In the case of a positive CT examination, this allows therapy to be started immediately and reduces complications. However, we suggest performing an elective MRI examination in negative cases in which pathological findings are hard to diagnose with CT alone.

Indexed as

DiscitisEmergency Service, HospitalHumansMagnetic Resonance ImagingMultidetector Computed TomographySensitivity and Specificitymagnetic resonance imaging (MRI)multi-detector computer tomography (MDCT)spondylodiscitis

Identifiers

PMID35894025
PMCPMC9332551
OpenAlexW4288180058

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.