Evidence map›Paper›PMID 35893921›Full record

ArticleNutrients2022

Vitamin D and the Ability to Produce 1,25(OH)

Juhi Arora, Devanshi R Patel, McKayla J Nicol, Cassandra J Field, Katherine H Restori, Jinpeng Wang, Nicole E Froelich, Bhuvana Katkere, Josey A Terwilliger, Veronika Weaver and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Highlights from the 24th workshop on vitamin D in Austin, September 2022.The Journal of steroid biochemistry and molecular biology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Juhi AroraDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-2356-0559
Devanshi R PatelDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
McKayla J NicolDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Cassandra J FieldDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Katherine H RestoriDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Jinpeng WangDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Nicole E FroelichDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Bhuvana KatkereDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Josey A TerwilligerDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Veronika WeaverDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Erin LuleyAnimal Diagnostic Laboratory, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0001-7619-0793
Kathleen KellyAnimal Diagnostic Laboratory, The Pennsylvania State University, University Park, PA 16802, USA.
Girish S KirimanjeswaraDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Troy C SuttonDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-7880-4784
Margherita T CantornaDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Pennsylvania State University · US

Funding

Vitamin D Fluctuations and the Mucosal Immune ResponseR01AT005378 · NCCIH · PENNSYLVANIA STATE UNIVERSITY, THE · PI CANTORNA, MARGHERITA T · 2009 to 2020
$4.1M
Research Training in Physiological Adaptations to StressT32GM108563 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CANTORNA, MARGHERITA T, KORZICK, DONNA HOPE · 2014 to 2023
$2.2M
Regulation of B cells by SeleniumR01AI123521 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI KIRIMANJESWARA, GIRISH S · 2016 to 2020
$2.0M
Integrative Analysis of Metabolic Phenotypes (IAMP) Predoctoral Training ProgramT32DK120509 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI PATTERSON, ANDREW, PERDEW, GARY H. · 2020 to 2024
$781k
NCCIH NIH HHS R01 AT005378NIAID NIH HHS R01 AI123521NIDDK NIH HHS T32 DK120509NIGMS NIH HHS T32 GM108563NIH HHS R01AI123521NIH HHS R01AT005378NIH HHS T32GM108563
6 · The paper itself

Abstract

Vitamin D supplementation is linked to improved outcomes from respiratory virus infection, and the COVID-19 pandemic renewed interest in understanding the potential role of vitamin D in protecting the lung from viral infections. Therefore, we evaluated the role of vitamin D using animal models of pandemic H1N1 influenza and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. In mice, dietary-induced vitamin D deficiency resulted in lung inflammation that was present prior to infection. Vitamin D sufficient (D+) and deficient (D-) wildtype (WT) and D+ and D- Cyp27B1 (Cyp) knockout (KO, cannot produce 1,25(OH)

Indexed as

COVID-19Influenza A Virus, H1N1 SubtypeInfluenza, HumanVitamin D DeficiencyAnimalsHumansLungMicePandemicsSARS-CoV-2Vitamin DVitaminsVitamin DVitaminsinflammationinfluenzalungSARS-CoV-2vitamin D

Identifiers

PMID35893921
PMCPMC9332570
OpenAlexW4288068828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.