ArticleNutrients2022
Association between Dietary Niacin Intake and Migraine among American Adults: National Health and Nutrition Examination Survey.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.
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Who cites it
104 citing papers in PubMed, 160 citations in OpenAlex.
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- Serum albumin and hypertension: The mediating roles of BMI, C-reactive protein and extracellular fluid.Asia Pacific journal of clinical nutrition · 2026Article
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- A Study of the Relationship Between Serum Albumin-Corrected Fructosamine and Type 2 Diabetic Retinopathy.Journal of diabetes research · 2026Article
- Negative association between serum lutein/zeaxanthin levels and migraine in American adults: a retrospective study from NHANES.Archives of medical science : AMS · 2026Article
- Association between carbohydrate consumption and self-assessed severe headache or migraine among American adults.Journal of nutritional science · 2026Article
- Association between a dietary index for gut microbiota and frailty in U.S. adults aged 40 and older: evidence from NHANES 1999-2018.Journal of health, population, and nutrition · 2025Article
- The positive association between evening or night work schedules and coronary heart disease or angina among U.S. adults: A cross-sectional study.American journal of preventive cardiology · 2025Article
- The association of ZJU index with bowel health in US participants: a cross-sectional study.European journal of medical research · 2025Article
- Exploring the impact of dietary theobromine on endometriosis risk: Evidence from Mendelian randomization and NHANES data.Medicine · 2025Observational
- The association between social factors and migraine or severe headache in men: a secondary analysis of national population-based studies with machine learning models.The journal of headache and pain · 2025Article
44 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
Migraine is related to brain energy deficiency. Niacin is a required coenzyme in mitochondrial energy metabolism. However, the relationship between dietary niacin and migraines remains uncertain. We aimed to evaluate the relationship between dietary niacin and migraine. This study used cross-sectional data from people over 20 years old who took part in the National Health and Nutrition Examination Survey between 1999 and 2004, collecting details on their severe headaches or migraines, dietary niacin intake, and several other essential variables. There were 10,246 participants, with 20.1% (2064/10,246) who experienced migraines. Compared with individuals with lower niacin consumption Q1 (≤12.3 mg/day), the adjusted OR values for dietary niacin intake and migraine in Q2 (12.4−18.3 mg/day), Q3 (18.4−26.2 mg/day), and Q4 (≥26.3 mg/day) were 0.83 (95% CI: 0.72−0.97, p = 0.019), 0.74 (95% CI: 0.63−0.87, p < 0.001), and 0.72 (95% CI: 0.58−0.88, p = 0.001), respectively. The association between dietary niacin intake and migraine exhibited an L-shaped curve (nonlinear, p = 0.011). The OR of developing migraine was 0.975 (95% CI: 0.956−0.994, p = 0.011) in participants with niacin intake < 21.0 mg/day. The link between dietary niacin intake and migraine in US adults is L-shaped, with an inflection point of roughly 21.0 mg/day.
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