Evidence map›Paper›PMID 35893855›Full record

ReviewNutrients2022

Health-Promoting and Therapeutic Attributes of Milk-Derived Bioactive Peptides.

Mrinal Samtiya, Sweta Samtiya, Prarabdh C Badgujar, Anil Kumar Puniya, Tejpal Dhewa, Rotimi E Aluko

Abstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mrinal SamtiyaDepartment of Nutrition Biology, School of Interdisciplinary and Applied Sciences, Central University of Haryana, Mahendergarh 123031, Haryana, India.ORCID 0000-0001-7413-1685
Sweta SamtiyaTrained Graduate Teacher (TGT) Science, Kendriya Vidyalaya No.2, Jalahalli East, Bengaluru 560014, Karnataka, India.
Prarabdh C BadgujarDepartment of Food Science and Technology, National Institute of Food Technology Entrepreneurship and Management, Kundli, Sonipat 131028, Haryana, India.
Anil Kumar PuniyaDairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal 132001, Haryana, India.ORCID 0000-0003-0043-5330
Tejpal DhewaDepartment of Nutrition Biology, School of Interdisciplinary and Applied Sciences, Central University of Haryana, Mahendergarh 123031, Haryana, India.ORCID 0000-0002-9129-4520
Rotimi E AlukoDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0002-9025-2513

Funding

Natural Sciences and Engineering Research Council RGPIN 2018-06019
6 · The paper itself

Abstract

Milk-derived bioactive peptides (BAPs) possess several potential attributes in terms of therapeutic capacity and their nutritional value. BAPs from milk proteins can be liberated by bacterial fermentation, in vitro enzymatic hydrolysis, food processing, and gastrointestinal digestion. Previous evidence suggested that milk protein-derived BAPs have numerous health-beneficial characteristics, including anti-cancerous activity, anti-microbial activity, anti-oxidative, anti-hypertensive, lipid-lowering, anti-diabetic, and anti-osteogenic. In this literature overview, we briefly discussed the production of milk protein-derived BAPs and their mechanisms of action. Milk protein-derived BAPs are gaining much interest worldwide due to their immense potential as health-promoting agents. These BAPs are now used to formulate products sold in the market, which reflects their safety as natural compounds. However, enhanced commercialization of milk protein-derived BAPs depends on knowledge of their particular functions/attributes and safety confirmation using human intervention trials. We have summarized the therapeutic potentials of these BAPs based on data from in vivo and in vitro studies.

Indexed as

MilkMilk ProteinsAnimalsFermentationHumansHydrolysisPeptidesMilk ProteinsPeptidesanti-diabeticanti-hypertensiveanti-inflammationbioactive peptidesmilk proteinstherapeutic potentials

Identifiers

PMID35893855
PMCPMC9331789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.