Evidence map›Paper›PMID 35893831›Full record

ArticleVaccines2022

Investigating the Role of Antigen Orientation on the Immune Response Elicited by

Renzo Alfini, Brunella Brunelli, Erika Bartolini, Martina Carducci, Enrico Luzzi, Francesca Ferlicca, Scilla Buccato, Barbara Galli, Paola Lo Surdo, Maria Scarselli and 7 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Outer Membrane Vesicle Vaccine Platforms.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  4. Outer Membrane Vesicle Vaccine Platforms.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Renzo AlfiniGSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.ORCID 0000-0001-7103-0723
Brunella BrunelliGSK, 53100 Siena, Italy.
Erika BartoliniGSK, 53100 Siena, Italy.ORCID 0000-0003-4536-2630
Martina CarducciGSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.ORCID 0000-0001-6633-567X
Enrico LuzziGSK, 53100 Siena, Italy.
Francesca FerliccaGSK, 53100 Siena, Italy.
Scilla BuccatoGSK, 53100 Siena, Italy.
Barbara GalliGSK, 53100 Siena, Italy.
Paola Lo SurdoGSK, 53100 Siena, Italy.
Maria ScarselliGSK, 53100 Siena, Italy.
Giacomo RomagnoliGSK, 53100 Siena, Italy.
Elena CartocciGSK, 53100 Siena, Italy.
Domenico MaioneGSK, 53100 Siena, Italy.
Silvana SavinoGSK, 53100 Siena, Italy.
Francesca NecchiGSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
Isabel DelanyGSK, 53100 Siena, Italy.
Francesca MicoliGSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.
Toscana Life Sciences · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GMMA are outer membrane vesicles (OMVs) released from Gram-negative bacteria genetically modified to enhance OMVs formation that have been shown to be optimal systems to enhance immunogenicity of protein antigens. Here, we selected

Indexed as

conjugationGMMANeisseria meningitidisouter membrane vesicles

Identifiers

PMID35893831
PMCPMC9331691
OpenAlexW4288178721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.