ArticleJournal of clinical medicine2022
Macroscopic Synovial Inflammation Correlates with Symptoms and Cartilage Lesions in Patients Undergoing Arthroscopic Partial Meniscectomy: A Clinical Study.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 35 citations in OpenAlex.
- Sagittal Tibial Tunnel Angle Is Associated with Meniscal Extrusion and Clinical Outcomes Following Transtibial Pull-Out Repair of Medial Meniscus Posterior Root Tears.Medicina (Kaunas, Lithuania) · 2026Article
- Linking meniscal pathology to Baker's cyst formation: the role of tear type, location and chondral damage.BMC musculoskeletal disorders · 2026Article
- Meniscal repair versus resection: Integrating pain mediator profiles with functional outcomes in a comparative effectiveness study.Medicine · 2026Article
- Rethinking meniscal repair in patients over 40: Extending the boundaries of joint preservation.World journal of methodology · 2026Review
- Age-Dependent Meniscal and Chondral Damage in Eastern European Women Undergoing First-Time Knee Arthroscopy.Healthcare (Basel, Switzerland) · 2025Article
- Musculoskeletal Diseases: From Molecular Basis to Therapy (Volume II).Biomedicines · 2025Article
- Lateral unicompartmental knee arthroplasty is an effective procedure for lateral post-meniscectomy knee osteoarthritis: a case-control study at a mean 7-year follow-up.Journal of orthopaedic surgery and research · 2025Article
- Impact of time between meniscal injury and isolated meniscus repair on post-operative outcomes: A systematic review.World journal of clinical cases · 2025Article
- Comprehensive Analysis of Programmed Cell Death-Related Genes in Diagnosis and Synovitis During Osteoarthritis Development: Based on Bulk and Single-Cell RNA Sequencing Data.Journal of inflammation research · 2025Article
- Exploring the Analgesic Effect of Acupuncture on Knee Osteoarthritis Based on MLT/cAMP/PKA/CREB Signaling Pathway.Journal of inflammation research · 2025Article
- Body roundness index and the risk of knee osteoarthritis: evidence from the China Health and Retirement Longitudinal Study.Frontiers in nutrition · 2025Article
- Association between visceral adiposity index and osteoarthritis in U.S. adults aged 50 and older: a cross-sectional study.Frontiers in nutrition · 2025Article
- Association between relative fat mass and osteoarthritis in American adults.Frontiers in nutrition · 2025Article
- Intermittent fasting in osteoarthritis: from mechanistic insights to therapeutic potential.Frontiers in nutrition · 2025Review
- Advanced nanoparticles for osteoarthritis: a review.Frontiers in medicine · 2025Review
- Functions of Macrophages, T Cells, and Neutrophils in the Synovial Microenvironment of Osteoarthritis.Journal of inflammation research · 2025Review
- Association between obesity indices, insulin resistance markers, and osteoarthritis in middle-aged and elderly Chinese adults.Frontiers in nutrition · 2025Article
- Correlation of meniscus tear type with synovial inflammation and the therapeutic potential of docosapentaenoic acid.BMC musculoskeletal disorders · 2024Article
- Changes in the Serum Metabolome in an Inflammatory Model of Osteoarthritis in Rats.International journal of molecular sciences · 2024Article
- Arthroscopic Linear Chain Fixation for the Treatment of Medial Meniscus Posterior Root Tear: A Case Study.Orthopaedic surgery · 2024Article
Corrections and comments
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Authors and funding
16 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThe aim of the study was to examine the relationship among patients' characteristics, intraoperative pathology and pre/post-operative symptoms in a cohort of patients undergoing arthroscopic partial meniscectomy for symptomatic meniscal tears.
methodsClinical data were collected (age, sex, body mass index, time to surgery, trauma). Intraoperative cartilage pathology was assessed with Outerbridge score. Meniscal tears were graded with the ISAKOS classification. Synovial inflammation was scored using the Macro-score. Patient symptoms were assessed pre/post-operatively using the KOOS instrument.
resultsIn the series of 109 patients (median age 47 years), 50% of the meniscal tears were traumatic; 85% of patients showed mild to moderate synovitis; 52 (47.7%) patients had multiple cartilage defects and 31 (28.4%) exhibited a single focal chondral lesion. Outerbridge scores significantly correlated with patient age, BMI and synovial inflammation. There was a correlation between severity of chondral pathology and high-grade synovial hyperplasia. Pre-operative KOOS correlated with BMI, meniscal degenerative changes and symptom duration. Obesity, time to surgery, presence of high-grade synovial hyperplasia and high-grade cartilage lesions were independent predictors of worse post-operative pain and function.
conclusionWe demonstrated that pre-operative symptoms and post-operative outcomes correlate with synovitis severity and cartilage pathology, particularly in old and obese patients that underwent arthroscopic partial meniscectomy. Importantly, patients with a degenerative meniscal pattern and with longer time to surgery experienced more severe cartilage damage and, consequentially, pain and dysfunction. These findings are fundamental to identify patients suitable for earlier interventions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.