Evidence map›Paper›PMID 35893397›Full record

ArticleJournal of clinical medicine2022

Ectopic Prostate Tissue in the Uterine Cervix of a Female with Non-Classic Congenital Adrenal Hyperplasia-A Case Report.

Lea Tschaidse, Matthias K Auer, Ilja Dubinski, Christian Lottspeich, Hanna Nowotny, Heinrich Schmidt, Nadezda Gut, Nicole Reisch

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lea TschaidseMedizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, 80336 Munich, Germany.
Matthias K AuerMedizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, 80336 Munich, Germany.
Ilja DubinskiDepartment of Pediatric Endocrinology, Dr. von Haunersches Children's Hospital, Klinikum der Universität München, LMU München, 80336 Munich, Germany.
Christian LottspeichMedizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, 80336 Munich, Germany.ORCID 0000-0002-1770-4392
Hanna NowotnyMedizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, 80336 Munich, Germany.
Heinrich SchmidtDepartment of Pediatric Endocrinology, Dr. von Haunersches Children's Hospital, Klinikum der Universität München, LMU München, 80336 Munich, Germany.
Nadezda GutZentrum für Pathologie Allgäu (ZfPA), Medizinisches Versorgungzentrum am Klinikum Kempten, 87439 Kempten, Germany.
Nicole ReischMedizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, 80336 Munich, Germany.
LMU Klinikum · DELudwig-Maximilians-Universität München · DEKempten University of Applied Sciences · DE

Funding

Deutsche Forschungsgemeinschaft 314061271-TRR 205Deutsche Forschungsgemeinschaft 325768017Eva Luise und Horst Köhler Stiftung & Else Kröner-Fresenius-Stiftung 2019_KollegSE.03German Ministry of Health 2519FSB503International Fund raising Congenital Adrenal Hyperplasia/European Society for Pediatric Endocrinology project 2019
6 · The paper itself

Abstract

introductionThe occurrence of ectopic prostate tissue in the female genital tract is rare and has only been described sporadically. The origin of these lesions is unclear, but their appearance seems to be associated with various forms of androgen excess, including androgen therapy for transgender treatment or disorders of sex development, such as classic congenital adrenal hyperplasia (CAH). This is the first described case of ectopic prostate tissue in the cervix uteri of a 46,XX patient with a confirmed diagnosis of non-classic CAH due to 21-OHD and a history of mild adrenal androgen excess. CASE PRESENTATION: We describe a 34-year-old patient with a genetic diagnosis of non-classic CAH due to 21-hydroxylase deficiency (21-OHD) with a female karyo- and phenotype and a history of mild adrenal androgen excess. Due to dysplasia in the cervical smear, conization had to be performed, revealing ectopic prostate tissue in the cervix uteri of the patient.

conclusionsAn association between androgen excess and the occurrence of prostate tissue is likely and should therefore be considered as a differential diagnosis for atypical tissue in the female genital tract.

Indexed as

21-hydroxylase deficiencyandrogen excessectopic prostate tissuehyperandrogenemiavirilization

Identifiers

PMID35893397
PMCPMC9331952
OpenAlexW4287837718

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.