Evidence map›Paper›PMID 35893396›Full record

ArticleJournal of clinical medicine2022

Primary Amenorrhea with Apparently Absent Uterus: A Report of Three Cases.

Eva Porsius, Marian Spath, Kirsten Kluivers, Willemijn Klein, Hedi Claahsen-van der Grinten

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eva PorsiusDepartment of Pediatric Endocrine Disease, Amalia Children's Hospital, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0001-6470-6123
Marian SpathDepartment of Obstetrics and Gynaecology, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
Kirsten KluiversDepartment of Obstetrics and Gynaecology, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
Willemijn KleinDepartment of Medical Imaging, Radiology, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0003-4309-533X
Hedi Claahsen-van der GrintenDepartment of Pediatric Endocrine Disease, Amalia Children's Hospital, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.ORCID 0000-0003-0181-0403
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe apparent absence of a uterus upon imaging women with primary amenorrhea appears to lead to a high risk of misdiagnosis, which will lead to significant mental distress in patients. CASE: Three young females with primary amenorrhea were referred with a diagnosis of Mayer-Rokitansky-Kuster-Hauser syndrome based on radiological findings of an apparently absent uterus. In two patients, the absence of the uterus could be confirmed, but with various diagnoses. The other patient had a normal but unstimulated uterus due to her hypoestrogenic state. SUMMARY AND

conclusionThe presented cases illustrate the broad differential diagnoses and the specific pitfalls of primary amenorrhea with an apparently absent uterus upon imaging. A well-established diagnosis was only possible through a thorough correlation of imaging findings with clinical history, biochemical findings and physical examination.

Indexed as

absent uterusDSDfemale genital malformationsMüllerian agenesisprimary amenorrhea

Identifiers

PMID35893396
PMCPMC9331643
OpenAlexW4287837512

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.