Evidence map›Paper›PMID 35893313›Full record

ArticleJournal of personalized medicine2022

Psychological Aspects of Syncopes and Possible Association with Recurrency-The Role of Implantable Loop Recorders.

Kevin Willy, Christian Ellermann, Sarah Syring, Benjamin Rath, Florian Reinke, Daniela Willy, Julian Wolfes, Felix K Wegner, Lars Eckardt, Julia Köbe and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kevin WillyDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.ORCID 0000-0003-1259-3213
Christian EllermannDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.
Sarah SyringDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.
Benjamin RathDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.
Florian ReinkeDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.
Daniela WillyDepartment of Obstetrics and Gynecology, University Hospital Münster, 48419 Münster, Germany.
Julian WolfesDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.
Felix K WegnerDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.ORCID 0000-0001-9087-645X
Lars EckardtDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.
Julia KöbeDepartment for Cardiology II: Electrophysiology, University Hospital Münster, Klinik für Kardiologie II: Rhythmologie, Albert-Schweitzer-Campus 1 Gebäude A1, D-48149 Münster, Germany.ORCID 0000-0002-5877-352X
Nexhmedin MorinaDepartment of Psychology, University of Münster, 48419 Münster, Germany.
University Hospital Münster · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syncopes are a very common phenomenon and have a high recurrence rate. The differentiation between the psychogenic and physical, especially of arrhythmic origin, remains difficult. In many cases, an implantable loop recorder is used for the detection of possible arrhythmias, leading to syncopes. Yet, the existing literature suggests that psychological factors may play a significant role in recurrent syncopes. We aimed at analyzing the potential role of several psychological factors on the recurrence of arrhythmic or non-arrhythmic syncopes. Methods and results: A total of 119 patients, who had received an implantable loop recorder for recurrent syncopes at our center between 01/2018 and 12/2021, participated in this retrospective cohort study. Anxiety, depression and quality of life were assessed using extensively validated questionnaires (GAD-7, PHQ-9 and SF-12). The mean follow-up after loop recorder implantation was 710 ± 430 days and 50% of patients were female. The mean patient age was 54.8 ± 18.6 years. Most patients had no evidence of structural heart disease (84%), and normal LV function (92%). A statistical analysis revealed that the presence of structural heart disease was the strongest predictor for arrhythmic syncope during follow-up. In patients with non-arrhythmic syncopes, we found significantly higher levels of anxiety (GAD-7 score: 2.5 ± 2.6 vs. 4.8 ± 4.3) and depression (PHQ-9 score: 3.9 ± 3.6 vs. 6.8 ± 5.1), and a lower quality of life (SF-12 score: 33.7 ± 6.4 vs. 29.6 ± 7.8). Discussion: We identified factors as contributors to a better identification of patients at risk for arrhythmic as well as non-arrhythmic syncopes. Especially anxious or depressive symptoms may hinted at non-arrhythmic causes of syncope. However, the study was limited by its retrospective design and low patient number. Further trials should likewise combine the diagnostic yield of loop recorders with psychometric evaluations before implantation and combine it with additional diagnostic measures, such as video monitoring, to further examine the role of psychological factors in the pathomechanism and treatment of syncope.

Indexed as

arrhythmiaILRloop recordermental healthmonitoringsyncope

Identifiers

PMID35893313
PMCPMC9332765
OpenAlexW4288041885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.