ReviewJournal of cardiovascular development and disease2022
Pulmonary Embolism in Women: A Systematic Review of the Current Literature.
Review in Journal of cardiovascular development and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Sex as a prognostic factor for mortality in adults with acute symptomatic pulmonary embolism.The Cochrane database of systematic reviews · 2025Pooled it
- Epidemiology, Risk Factors, and Mortality in Unprovoked and Provoked Pulmonary Embolism-A Single-Center Retrospective Study in the Israeli Population: Gender and Ethnic Differences.Epidemiologia (Basel, Switzerland) · 2026Article
- Pulmonary embolism mortality in the United States: a nationwide analysis.Journal of thrombosis and thrombolysis · 2026Article
- Trends in pulmonary embolism mortality among older adults with lung cancer in the united States, 1999-2020.Journal of thrombosis and thrombolysis · 2026Article
- Inpatient Characteristics and Outcomes of Venous Thromboembolism Among Children and Adolescents.JAMA network open · 2026Article
- The incidence and associated factors of pulmonary embolism after cardiac surgery: A retrospective nationwide inpatient sample database study.American heart journal plus : cardiology research and practice · 2026Article
- Analysis of the Phenotype and Gene Mutations of Two Families With Combined Mutations of Anticoagulant Protein Genes.Molecular genetics & genomic medicine · 2026Article
- Sex Differences as Predictors of In-Hospital Outcome in Patients with Acute Pulmonary Embolism.Journal of clinical medicine · 2026Article
- Disparities and trends in pulmonary embolism mortality with and without obesity: a nationwide US analysis.Research and practice in thrombosis and haemostasis · 2025Article
- Gender disparities in high-risk pulmonary embolism: a nationwide analysis of management strategies and clinical outcomes.BMC cardiovascular disorders · 2025Article
- A Retrospective Perspective: Evaluating Pulmonary Embolism Risk Factors and Survival Trends.Annals of African medicine · 2025Article
- Observational
- Efficient management of pulmonary embolism diagnosis using a two-step interconnected machine learning model based on electronic health records data.Health information science and systems · 2024Article
- CT-Derived Features as Predictors of Clot Burden and Resolution.Bioengineering (Basel, Switzerland) · 2024Article
- Identifying high-risk groups for deep vein thrombosis after primary total knee arthroplasty using preoperative Caprini scores and D-dimer levels.Journal of orthopaedic surgery and research · 2024Article
- Validation of a pulmonary embolism risk assessment model in gynecological inpatients : Clinical trial: A single-center, retrospective study.Thrombosis journal · 2024Article
- A Comprehensive Review of Risk Factors and Thrombophilia Evaluation in Venous Thromboembolism.Journal of clinical medicine · 2024Review
- Assessment of the Utilization of Validated Diagnostic Predictive Tools and D-Dimer in the Evaluation of Pulmonary Embolism: A Single-Center Retrospective Cohort Study from a Public Hospital in New York City.Journal of clinical medicine · 2023Article
- Women's Cardiovascular Health: Prioritizing the Majority Minority.Journal of cardiovascular development and disease · 2023Article
- Exploring Risk Factors for Lower Extremity Deep Vein Thrombosis Patients with Co-existing Pulmonary Embolism Based on Multiple Logistic Regression Model.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease is the leading cause of death in women. Pulmonary embolism (PE) is the third most-common cause of cardiovascular death, after myocardial infarction (MI) and stroke. We aimed to evaluate the attributes and outcomes of PE specifically in women and explore sex-based differences. We conducted a systematic review of the literature using electronic databases PubMed and Embase up to 1 April 2022 to identify studies investigating PE in women. Of the studies found, 93 studies met the eligibility criteria and were included. The risk of PE in older women (especially >40 years of age) superseded that of age-matched men, although the overall age- and sex-adjusted incidence of PE was found to be lower in women. Risk factors for PE in women included age, rheumatologic disorders, hormone replacement therapy or oral contraceptive pills, pregnancy and postpartum period, recent surgery, immobilization, trauma, increased body mass index, obesity, and heart failure. Regarding pregnancy, a relatively higher incidence of PE has been observed in the immediate postpartum period compared to the antenatal period. Women with PE tended to be older, presented more often with dyspnea, and were found to have higher NT-proBNP levels compared to men. No sex-based differences in in-hospital mortality and 30-day all-cause mortality were found. However, PE-related mortality was higher in women, particularly in hemodynamically stable patients. These differences form the basis of future research and outlets for reducing the incidence, morbidity, and mortality of PE in women.
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Registered trials
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