Evidence map›Paper›PMID 35893069›Full record

ArticleGenes2022

Molecular Insights into the Role of Pathogenic nsSNPs in

Abid Ali Shah, Marryam Amjad, Jawad-Ul Hassan, Asmat Ullah, Arif Mahmood, Huiyin Deng, Yasir Ali, Fouzia Gul, Kun Xia

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. ACS omega · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Structural Evaluation and Conformational Dynamics ofBioengineering (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Abid Ali ShahCenter for Medical Genetics and Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha 410013, China.ORCID 0000-0001-7740-9427
Marryam AmjadDistrict Headquarter (DHQ) Hospital, Faisalabad 38000, Punjab, Pakistan.
Jawad-Ul HassanAllied Hospital, Faisalabad 38000, Punjab, Pakistan.
Asmat UllahNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-5715-3425
Arif MahmoodCenter for Medical Genetics and Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha 410013, China.ORCID 0000-0002-0309-1230
Huiyin DengDepartment of Anesthesiology, The Third Xiangya Hospital of Central South University, Changsha 410013, China.
Yasir AliNational Center for Bioinformatics, Quaid-i-Azam University, Islamabad 45320, Pakistan.ORCID 0000-0002-1230-1666
Fouzia GulNational Center for Bioinformatics, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Kun XiaCenter for Medical Genetics and Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha 410013, China.
Central South University · CNQuaid-i-Azam University · PKAllied Hospital · PKFarooq Hospital · PKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The GluN2B subunit of N-methyl-D-aspartate receptors plays an important role in the physiology of different neurodevelopmental diseases. Genetic variations in the GluN2B coding gene (

Indexed as

Neurodevelopmental DisordersPolymorphism, Single NucleotideReceptors, N-Methyl-D-AspartateHumansMutationPhylogenyNR2B NMDA receptorReceptors, N-Methyl-D-AspartateDevelopmental delayGRIN2BLennox–Gastaut syndromeMolecular dynamics simulationNeurodevelopmental disordersSNPs

Identifiers

PMID35893069
PMCPMC9394290
OpenAlexW4288040285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.