Evidence map›Paper›PMID 35893064›Full record

ArticleGenes2022

CRISPR DNA Base Editing Strategies for Treating Retinitis Pigmentosa Caused by Mutations in

Maria Kaukonen, Michelle E McClements, Robert E MacLaren

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Gene Therapy Strategies for the Treatment of Bestrophinopathies.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maria KaukonenNuffield Department of Clinical Neuroscience, University of Oxford, Oxford OX3 9DU, UK.ORCID 0000-0002-2146-4694
Michelle E McClementsNuffield Department of Clinical Neuroscience, University of Oxford, Oxford OX3 9DU, UK.ORCID 0000-0002-2941-4464
Robert E MacLarenNuffield Department of Clinical Neuroscience, University of Oxford, Oxford OX3 9DU, UK.
University of Oxford · GB

Funding

Medical Research Council MC_PC_18059
6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is the most common group of inherited retinal degenerations and pathogenic variants in the

Indexed as

Gene EditingRetinitis PigmentosaRhodopsinDNAGenes, DominantHumansMutationStaphylococcus aureusDNARhodopsinbase editinginherited retinal dystrophyretinitis pigmentosaRHOrhodopsin

Identifiers

PMID35893064
PMCPMC9330713
OpenAlexW4288041435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.