Evidence map›Paper›PMID 35893055›Full record

ArticleGenes2022

Cadmium Ecotoxic Effects on Embryonic

Beatriz Mizoguchi, Nicholas E Topping, Andrew M Lavin, Nicole Valenzuela

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Beatriz MizoguchiDepartment of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA 50011, USA.
Nicholas E ToppingDepartment of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA 50011, USA.
Andrew M LavinDepartment of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA 50011, USA.
Nicole ValenzuelaDepartment of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0003-1148-631X
Iowa State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temperature-dependent sex determination (TSD) decides the sex fate of an individual based on incubation temperature. However, other environmental factors, such as pollutants, could derail TSD sexual development. Cadmium is one such contaminant of soils and water bodies known to affect DNA methylation, an epigenetic DNA modification with a key role in sexual development of TSD vertebrate embryos. Yet, whether cadmium alters DNA methylation of genes underlying gonadal formation in turtles remains unknown. Here, we investigated the effects of cadmium on the expression of two gene regulators of TSD in the painted turtle,

Indexed as

TurtlesAnimalsAromataseCadmiumDNA MethylationFemaleGonadsMaleAromataseCadmiumcadmiumdevelopmental disruptorsecotoxicology of endocrineepigenetic modification by DNA methylationreptile vertebratessex determinationsexual testis and ovary developmenttranscriptional

Identifiers

PMID35893055
PMCPMC9331853
OpenAlexW4287009859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.