Evidence map›Paper›PMID 35893052›Full record

ArticleGenes2022

A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish.

Ankit Sabharwal, Jarryd M Campbell, Tanya L Schwab, Zachary WareJoncas, Mark D Wishman, Hirotaka Ata, Wiebin Liu, Noriko Ichino, Danielle E Hunter, Jake D Bergren and 9 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Comparative Mitogenomics ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Review
  4. Complete mitochondrial genome of an abyssal cusk-eelMitochondrial DNA. Part B, Resources · 2025
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Ankit SabharwalDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-4355-0355
Jarryd M CampbellDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Tanya L SchwabDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Zachary WareJoncasDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Mark D WishmanDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Hirotaka AtaDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Wiebin LiuDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Noriko IchinoDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Danielle E HunterDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Jake D BergrenDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Mark D UrbanDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-9992-7820
Rhianna M UrbanDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Shannon R HolmbergDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Bibekananda KarDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0001-8794-1513
Alex CookDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Yonghe DingDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Xiaolei XuDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Karl J ClarkDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
Stephen C EkkerDepartment of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-0726-4212
Mayo Clinic · US

Funding

PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI Nicholas F. LaRusso · 2009 to 2026
$22.2M
Systematic Vertebrate Functional GenomicsR01GM063904 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI EKKER, STEPHEN CARL · 2001 to 2025
$10.7M
International Zebrafish Mutagenic Protein TrapR01HG006431 · NHGRI · MAYO CLINIC ROCHESTER · PI EKKER, STEPHEN CARL · 2011 to 2016
$3.3M
Conditional genetics and precision genome editing resources for ZebrafishR24OD036201 · OD · IOWA STATE UNIVERSITY · PI KARL J CLARK, Stephen Carl Ekker · 2024 to 2026
$3.0M
Systematic Vertebrate Functional GenomicsR56GM063904 · NIGMS · MAYO CLINIC ROCHESTER · PI EKKER, STEPHEN CARL · 2009 to 2010
$611k
NHGRI NIH HHS R01 HG006431NIDDK NIH HHS P30 DK084567NIGMS NIH HHS R01 GM063904NIGMS NIH HHS R56 GM063904NIH HHS R24 OD036201
6 · The paper itself

Abstract

Mitochondria are a dynamic eukaryotic innovation that play diverse roles in biology and disease. The mitochondrial genome is remarkably conserved in all vertebrates, encoding the same 37-gene set and overall genomic structure, ranging from 16,596 base pairs (bp) in the teleost zebrafish (

Indexed as

Genome, MitochondrialZebrafishAnimalsGenes, MitochondrialHumansMitochondriaGene Breaking Transposongene editingmitochondriamitochondrial disordersTALENzebrafish

Identifiers

PMID35893052
PMCPMC9331066
OpenAlexW4287009935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.