Evidence map›Paper›PMID 35892964›Full record

ArticleBiology2022

Targeting the Ubiquinol-Reduction (Q

Kangsa Amporndanai, Nattapon Pinthong, Paul M O'Neill, W David Hong, Richard K Amewu, Chandrakala Pidathala, Neil G Berry, Suet C Leung, Stephen A Ward, Giancarlo A Biagini and 2 more

Abstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Revisiting 2-Substituted-4(1Journal of medicinal chemistry · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Targeting Mitochondrial Function inInternational journal of molecular sciences · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Mitochondrial CytochromeTropical medicine and infectious disease · 2024
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kangsa AmporndanaiMolecular Biophysics Group, Institute of Systems, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, UK.
Nattapon PinthongMolecular Biophysics Group, Institute of Systems, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, UK.ORCID 0000-0002-0740-9496
Paul M O'NeillDepartment of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK.
W David HongDepartment of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK.
Richard K AmewuDepartment of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK.
Chandrakala PidathalaDepartment of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK.
Neil G BerryDepartment of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK.ORCID 0000-0003-1928-0738
Suet C LeungDepartment of Chemistry, University of Liverpool, Liverpool L69 7ZD, UK.
Stephen A WardCentre for Drugs and Diagnostics, Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.
Giancarlo A BiaginiCentre for Drugs and Diagnostics, Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK.ORCID 0000-0001-6356-6595
S Samar HasnainMolecular Biophysics Group, Institute of Systems, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, UK.
Svetlana V AntonyukMolecular Biophysics Group, Institute of Systems, Molecular and Integrative Biology, Faculty of Health and Life Sciences, University of Liverpool, Liverpool L69 7ZB, UK.ORCID 0000-0002-2779-9946

Funding

Medical Research Council MC_PC_17167Medical Research Council MR/L000644/1Medical Research Council MR/S00467X/1Medical Research Council MR/W002248/1Medical Research Council MR/W004356/1
6 · The paper itself

Abstract

Antimalarials targeting the ubiquinol-oxidation (Q

Indexed as

antimalarialatovaquonebc1 inhibitorcrystallographydrug resistancehomology modelingmitochondriamolecular modelingPlasmodium falciparumquinolone

Identifiers

PMID35892964
PMCPMC9330653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.