Evidence map›Paper›PMID 35892738›Full record

ReviewDiseases (Basel, Switzerland)2022

The 8th Wonder of the Cancer World: Esophageal Cancer and Inflammation.

Harleen Kaur Chela, Karthik Gangu, Hamza Ertugrul, Alhareth Al Juboori, Ebubekir Daglilar, Veysel Tahan

Open access · goldAbstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Barrett's esophagus: A review.World journal of gastrointestinal pathophysiology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Insights into the Relationship between Pentraxin-3 and Cancer.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Harleen Kaur ChelaDepartment of Gastroenterology, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0003-0658-1857
Karthik GanguDepartment of Medicine, Division of Hospital Medicine, University of Missouri, Columbia, MO 65201, USA.
Hamza ErtugrulDepartment of Gastroenterology, University of Missouri, Columbia, MO 65201, USA.
Alhareth Al JubooriDepartment of Gastroenterology, University of Missouri, Columbia, MO 65201, USA.
Ebubekir DaglilarDepartment of Gastroenterology, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0003-0622-1704
Veysel TahanDepartment of Gastroenterology, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0001-6796-9359
University of Missouri · USUniversity of Missouri Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer is a devastating malignancy which can be detected at an early stage but is more often diagnosed as an advanced process. It affects both men and women and inflicts the young and the elderly. There are multiple underlying factors involved in the pathogenesis of this cancer including inflammation. The interplay of these factors promotes inflammation through various mechanisms including the recruitment of pro-inflammatory cells, mediators such as cytokines, reactive oxygen species, and interleukins, among others. The presentation can vary widely with one of the most notable symptoms being dysphagia. Diagnosis is based on clinical symptomatology, imaging and endoscopy with biopsy. Once the diagnosis has been established, treatment and prognosis are based on the stage of the disease. This review outlines esophageal cancer and its link to inflammation in relation to pathogenesis, along with clinical features, diagnosis and treatment.

Indexed as

canceresophagusinflammationpathogenesispathology

Identifiers

PMID35892738
PMCPMC9326664
OpenAlexW4284706310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.