Evidence map›Paper›PMID 35892617›Full record

ArticleChildren (Basel, Switzerland)2022

Assessing Higher-Order Visual Processing in Cerebral Visual Impairment Using Naturalistic Virtual-Reality-Based Visual Search Tasks.

Claire E Manley, Christopher R Bennett, Lotfi B Merabet

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06067607 (Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment and Its Impact on Occupational Performance), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06067607 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment and Its Impact on Occupational Performance

TypeinterventionalSponsorRockhurst UniversityRan2023 to 2024Enrolled10ConditionsCortical/Cerebral Visual Impairment, Cerebral PalsyArmseye gaze technology
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

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  10. Adaptive functioning and relationship to visual behavior in children with cerebral/cortical visual impairment.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Claire E ManleyThe Laboratory for Visual Neuroplasticity, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
Christopher R BennettThe Laboratory for Visual Neuroplasticity, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.
Lotfi B MerabetThe Laboratory for Visual Neuroplasticity, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-8094-9536
Massachusetts Eye and Ear Infirmary · US

Funding

Neurophysiological Correlates of Visual Motion Processing in Cerebral Visual ImpairmentR01EY030973 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Lotfi Merabet · 2020 to 2026
$2.0M
Assessing Spatial Processing Deficits in Cerebral Visual Impairment (CVI) Using Virtual RealityR21EY030587 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI MERABET, LOTFI · 2019 to 2020
$477k
NEI NIH HHS R01 EY030973NEI NIH HHS R21 EY030587
6 · The paper itself

Abstract

Cerebral visual impairment (CVI) is a brain-based disorder associated with the maldevelopment of central visual pathways. Individuals with CVI often report difficulties with daily visual search tasks such as finding a favorite toy or familiar person in cluttered and crowded scenes. We developed two novel virtual reality (VR)-based visual search tasks combined with eye tracking to objectively assess higher order processing abilities in CVI. The first (virtual toybox) simulates a static object search, while the second (virtual hallway) represents a dynamic human search task. Participants were instructed to search for a preselected target while task demand was manipulated with respect to the presence of surrounding distractors. We found that CVI participants (when compared to age-matched controls) showed an overall impairment with visual search on both tasks and with respect to all gaze metrics. Furthermore, CVI participants showed a trend of worsening performance with increasing task demand. Finally, search performance was also impaired in CVI participants with normal/near normal visual acuity, suggesting that reduced stimulus visibility alone does not account for these observations. This novel approach may have important clinical utility in helping to assess environmental factors related to functional visual processing difficulties observed in CVI.

Indexed as

attentioncerebral visual impairment (CVI)eye trackinghigher order visual processingvirtual realityvisual perceptionvisual search

Identifiers

PMID35892617
PMCPMC9331719
OpenAlexW4288038132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.