ArticleBrain sciences2022
Patients with Methamphetamine Use Disorder Show Highly Utilized Proactive Inhibitory Control and Intact Reactive Inhibitory Control with Long-Term Abstinence.
Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Common and distinct patterns of brain activity alterations during inhibitory control in depression and psychostimulant users: a comparative meta-analysis of task-based fMRI studies.Psychological medicine · 2025Pooled it
- Double-blind, randomized clinical trial targeting theta oscillations with transcranial alternating current stimulation (tACS) for cognitive control in male methamphetamine patients.Molecular psychiatry · 2026Article
- Exercise-Induced Metaplasticity: Breaking the Addiction Cycle in Methamphetamine Use Disorder.Sports medicine - open · 2026Review
- Measurement of Impulsivity and Its Role in Drug Use Behaviours and Related Health, Harm and Treatment Outcomes Among People Who Use Illicit Drugs-A Scoping Review.International journal of mental health and addiction · 2026Article
- Effects of methamphetamine-induced sleep disruption on intradimensional/extradimensional attentional set-shifting in adult rhesus monkeys.The Journal of pharmacology and experimental therapeutics · 2025Article
- Individuals recently abstinent from methamphetamine show selective cognitive and behavioral differences when compared to age-matched controls.Frontiers in psychiatry · 2025Article
- Modeling methamphetamine use disorder and relapse in animals: short- and long-term epigenetic, transcriptional., and biochemical consequences in the rat brain.Neuroscience and biobehavioral reviews · 2023Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
Methamphetamine use disorder (MUD) is a chronic brain disorder that involves frequent failures of inhibitory control and relapses into methamphetamine intake. However, it remains unclear whether the impairment of inhibitory control in MUD is proactive, reactive or both. To address this issue, the current study used the conditional stop-signal task to assess proactive and reactive inhibitory control in 35 MUD patients with long-term abstinence and 35 matched healthy controls. The results showed that MUD patients with long-term abstinence had greater preparation costs than healthy controls, but did not differ in performance, implying a less efficient utilization of proactive inhibitory control. In contrast, MUD patients exhibited intact reactive inhibitory control; reactive but not proactive inhibitory control was associated with high sensation seeking in MUD patients with long-term abstinence. These findings suggest that proactive and reactive inhibitory control may be two different important endophenotypes of addiction in MUD patients with long-term abstinence. The current study provides new insight into the uses of proactive and reactive inhibitory control to effectively evaluate and precisely treat MUD patients with long-term abstinence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.