Evidence map›Paper›PMID 35892127›Full record

ArticleACS bio & med chem Au2022

Identification of Natural Product Sulfuretin Derivatives as Inhibitors for the Endoplasmic Reticulum Redox Protein ERO1α.

Brennan D Johnson, Sridhar Kaulagari, Wei-Chih Chen, Karen Hayes, Werner J Geldenhuys, Lori A Hazlehurst

Open access · goldAbstract read
In one paragraph

Article in ACS bio & med chem Au, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brennan D JohnsonCancer Center, School of Medicine, West Virginia University, Morgantown WV 26501.
Sridhar KaulagariModulation Therapeutics Inc, Morgantown WV 26506.
Wei-Chih ChenCancer Center, School of Medicine, West Virginia University, Morgantown WV 26501.
Karen HayesModulation Therapeutics Inc, Morgantown WV 26506.
Werner J GeldenhuysDepartment of Pharmaceutical Sciences, School of Pharmacy West Virginia University, Morgantown WV 26505.
Lori A HazlehurstCancer Center, School of Medicine, West Virginia University, Morgantown WV 26501.
West Virginia University · USModulation Therapeutics (United States) · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
West Virginia University Stroke COBREP20GM109098 · NIGMS · WEST VIRGINIA UNIVERSITY · PI HRUSKA, MARTIN · 2014 to 2024
$24.5M
WVU Flow Cytometry and Single Cell Core Facility (FCSCCF)P20GM121322 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Dominique Bollino · 2018 to 2026
$22.4M
Mechanism underpinning synergy with combined treatment of MTI-101 and Dexamethasone in Multiple MyelomaR44CA221554 · NCI · MODULATION THERAPEUTICS, INC. · PI HAZLEHURST, LORI · 2017 to 2020
$2.4M
Targeting CD44-mediated calcium signaling for the treatment of relapsed myelomaR01CA195727 · NCI · WEST VIRGINIA UNIVERSITY · PI HAZLEHURST, LORI A · 2015 to 2019
$1.7M
Mitotic Catastrophe in Tumor CellsR01CA095727 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RONINSON, IGOR B · 2002 to 2005
$1.2M
NCI NIH HHS R01 CA095727NCI NIH HHS R01 CA195727NCI NIH HHS R44 CA221554NIGMS NIH HHS P20 GM103434NIGMS NIH HHS P20 GM109098NIGMS NIH HHS P20 GM121322NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

The flavin adenine dinucleotide containing Endoplasmic Reticulum Oxidoreductase-1 α (ERO1α) catalyzes the formation of

Indexed as

ERO1αFADflavoenzymelung cancerPDIredox

Identifiers

PMID35892127
PMCPMC9312093
OpenAlexW4205581705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.