Evidence map›Paper›PMID 35892126›Full record

ReviewNon-coding RNA research2022

Functions of the bone morphogenetic protein signaling pathway through non-coding RNAs.

Ural Mukhametov, Sergey Lyulin, Dmitry Borzunov, Galina Sufianova, Alina Shumadalova, Daming Zhang, Ilgiz Gareev

Open access · goldAbstract readReview
In one paragraph

Review in Non-coding RNA research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  9. From mesenchymal niches to engineeredMaterials today. Bio · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Ural MukhametovRepublican Clinical Hospital. G.G. Kuvatova, Ufa, 450071, Russian Federation.
Sergey LyulinCarmel Medical Center, Chelyabinsk, 454080, Russian Federation.
Dmitry BorzunovUral State Medical University, Ekaterinburg, 620028, Russian Federation.
Galina SufianovaDepartment of Pharmacology, Tyumen State Medical University, Tyumen, Russia.
Alina ShumadalovaBashkir State Medical University, Ufa, Russian Federation.
Daming ZhangDepartment of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Ilgiz GareevРeoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation.
Bashkir State Medical University · RUHarbin Medical University · CNPeoples' Friendship University of Russia · RURepublican Clinical Hospital named after G.G. Kuvatova · RUTyumen State Medical University · RUUral State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone morphogenetic proteins (BMPs) are proteins of the transforming growth factor-β (TGF-β) family, which plays an important role in the formation of skeletal and cartilage tissue and their regeneration. BMPs play a key role in the formation of new blood vessels and promote the migration, proliferation, and differentiation of mesenchymal stem cells (MSCs) into chondroblasts and osteoblasts. It is known that malfunction of BMPs signaling can cause a disease state. Epigenetic regulation of expression plays a key role in the control of many cellular processes. Important participants in this regulation are non-coding RNAs (ncRNAs), which are RNA molecules that are not translated into proteins. The best known of these are microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs). In addition, the results of many studies make it possible to establish an unambiguous functional relationship between these ncRNAs. Being involved in the regulation of a large number of target genes responsible for the life of the cell, miRNAs, lncRNAs, and circRNAs are essential for the normal development and functioning of the body, and the violation of their functions accompanies the development of many pathophysiological processes including oncogenesis. In the present review, we discuss different insights into the regulation of BMPs signaling pathway by miRNAs, lncRNAs and circRNAs governed.

Indexed as

Biological processesBone morphogenetic proteinscircRNAslncRNAsmiRNAsOncogenesisOsteoporosis

Identifiers

PMID35892126
PMCPMC9287601
OpenAlexW4284990675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.