Evidence map›Paper›PMID 35892096›Full record

ArticleJournal of veterinary research2022

Protective Effects of

Mohamed A Elhady, Abdel Azeim A Khalaf, Marwa A Ibrahim, Eman I Hassanen, Rehab E Abdelrahman, Peter A Noshy

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
  6. Isolation of a novelFrontiers in microbiology · 2024
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mohamed A ElhadyDepartment of Toxicology and Forensic Medicine, Giza Egypt.
Abdel Azeim A KhalafDepartment of Toxicology and Forensic Medicine, Giza Egypt.
Marwa A IbrahimDepartment of Biochemistry and Metabolism, Giza Egypt.
Eman I HassanenDepartment of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza 12613, Egypt.
Rehab E AbdelrahmanDepartment of Toxicology and Forensic Medicine, Giza Egypt.
Peter A NoshyDepartment of Toxicology and Forensic Medicine, Giza Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Ochratoxin A (OTA) is a mycotoxin notably produced by Material and Methods: Day-old broiler chicks were divided equally into four groups of ten: control, OTA (0.5 mg/kg feed), BSFE product (1 mL/L water) and OTA + BSFE at the same concentrations. The chicks were vaccinated against avian influenza, Newcastle disease, and infectious bronchitis, and lymphoproliferation was induced in all birds by phytohaemagglutinin-P (PHA-P). Serum samples were taken before sacrifice and organ tissue samples were taken after, in which renal function biomarkers were assayed and the presence of OTA residue was evaluated by high-performance thin-layer chromatography. Protein markers of apoptosis were determined by qPCR, and tissue lesions were examined histopathologically. Results: Exposure to OTA significantly decreased the antibody response to the vaccines and the lymphoproliferative response to PHA-P, and significantly elevated the renal function indicators: serum urea, uric acid and creatinine. It also induced oxidative stress (reduced catalase activity and glutathione concentration), lipid peroxidation (increased malondialdehyde content), apoptosis (increased Conclusion: BSFE counters OTA-induced immunotoxicity and nephrotoxicity because of its content of carboxypeptidase and protease enzymes.

Indexed as

apoptosisBacillus subtiliscarboxypeptidasemycotoxinsoxidative stress

Identifiers

PMID35892096
PMCPMC9281517
OpenAlexW4283813880

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.