Evidence map›Paper›PMID 35892093›Full record

ArticleMolecular therapy. Nucleic acids2022

HIV-1 Tat and cocaine impact astrocytic energy reservoirs and epigenetic regulation by influencing the LINC01133-hsa-miR-4726-5p-NDUFA9 axis.

Mayur Doke, Jay P McLaughlin, James J Cai, Gurudutt Pendyala, Fatah Kashanchi, Mansoor A Khan, Thangavel Samikkannu

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. MIR4726Cell communication and signaling : CCS · 2025
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mayur DokeDepartment of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University, TX 78363, USA.
Jay P McLaughlinDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.
James J CaiVeterinary Integrative Biosciences, Texas A&M University, TAMU 4458, College Station, TX 77845, USA.
Gurudutt PendyalaDepartment of Anesthesiology, University of Nebraska Medical Center (UNMC), Omaha, NE 68198, USA.
Fatah KashanchiNational Center for Biodefense and Infectious Disease, Laboratory of Molecular Virology, George Mason University, Manassas, VA 20110, USA.
Mansoor A KhanDepartment of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University, TX 78363, USA.
Thangavel SamikkannuDepartment of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University, TX 78363, USA.
Texas A&M University · USGeorge Mason University · USUniversity of Florida · USUniversity of Nebraska Medical Center · US

Funding

Cocaine and HIV Influence Mitochondrial Epigenetics in Astrocytic NetworksR01DA044872 · NIDA · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI THANGAVEL, SAMIKKANNU · 2017 to 2021
$2.3M
NIDA NIH HHS R01 DA044872
6 · The paper itself

Abstract

Clinical research has proven that HIV-positive (HIV

Indexed as

cocaineenergy metabolismHIV-associated dementiahsa-miR-4726-5pLINC01133NDUFA9

Identifiers

PMID35892093
PMCPMC9307901
OpenAlexW4286432827

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.