Evidence map›Paper›PMID 35892086›Full record

ArticleMolecular therapy. Methods & clinical development2022

Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors.

Rosie J Munday, Tiziana Coradin, Rachael Nimmo, Yatish Lad, Stephen C Hyde, Kyriacos Mitrophanos, Deborah R Gill

Abstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Lentiviral Gene Therapy for Cystic Fibrosis: A Promising Approach and First-in-Human Trial.American journal of respiratory and critical care medicine · 2024
    Review
  8. Article
  9. Review
  10. Progress in Respiratory Gene Therapy.Human gene therapy · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rosie J MundayGene Medicine Research Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, John Radcliffe Hospital (Level 4), University of Oxford, Oxford OX3 9DU, UK.
Tiziana CoradinOxford Biomedica (UK) Ltd., Oxford OX4 6LT, UK.
Rachael NimmoOxford Biomedica (UK) Ltd., Oxford OX4 6LT, UK.
Yatish LadOxford Biomedica (UK) Ltd., Oxford OX4 6LT, UK.
Stephen C HydeGene Medicine Research Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, John Radcliffe Hospital (Level 4), University of Oxford, Oxford OX3 9DU, UK.
Kyriacos MitrophanosOxford Biomedica (UK) Ltd., Oxford OX4 6LT, UK.
Deborah R GillGene Medicine Research Group, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, John Radcliffe Hospital (Level 4), University of Oxford, Oxford OX3 9DU, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A lentiviral vector (LV) pseudotype derived from the fusion (F) and hemagglutinin-neuraminidase (HN) glycoproteins of a murine respirovirus (Sendai virus) facilitates efficient targeting of murine lung

Indexed as

air-liquid interfaceavian influenza virushemagglutininhuman airwaylectinlentiviral vectorpseudotypeSendai virussialic acidsialidase

Identifiers

PMID35892086
PMCPMC9304433

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.