ArticleInternational journal of clinical and health psychology : IJCHP
Transdiagnostic model of psychological factors and sex differences in depression in a large sample of Ecuador.
Article in International journal of clinical and health psychology : IJCHP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Psychological Capital and Mental Health in Ecuadorian University Students: The Mediating Role of Negative Stress.European journal of investigation in health, psychology and education · 2026Article
- Transdiagnostic processes in university mental health: the role of psychological inflexibility, impulsivity and stress in depression and life satisfaction using structural equation modeling.Frontiers in public health · 2026Article
- Psychometric evaluation of the Perceived Stress Scale (PSS-10) in Ecuadorian adults: evidence from a bifactor model and measurement invariance.Frontiers in psychology · 2026Article
- Integrating psychosocial health into disaster risk management: Insights from COVID-19 in Durán, Ecuador.PloS one · 2026Article
- Loneliness as a Public Health Challenge: A Systematic Review and Meta-Analysis to Inform Policy and Practice.European journal of investigation in health, psychology and education · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
Background/Objective: Depression represents a leading cause of disability and a major contributor to the overall global burden of disease with women systematically reporting a higher prevalence than men. This study aimed to examine the predictive value and relation of three transdiagnostic psychological factors (perceived stress, psychological inflexibility and loneliness) on depression and its sex differences for the general population in a large sample of Ecuador. Method: A non-probabilistic and non-clinical sample of 16.074 people from across Ecuador were online surveyed using a cross-sectional design. The structural equation model was based on scores from standardized questionnaires as measures of depression, psychological perceived stress, psychological inflexibility, and loneliness. Results: Women reported significantly higher levels of depression, mediated by differences in perceived stress, psychological inflexibility and loneliness. Perceived stress was the most important predictor of depression and mediated the effect of loneliness on depression. Complementarily, psychological inflexibility partially mediated the effect of perceived stress and loneliness on depression. The overall model accounted for the 78% of the total variance in depression. Conclusions: Results of this study provide a novel and robust transdiagnostic model of sex differences on depression and insights on how to design effective programs for preventing depression targeting modifiable transdiagnostic risk factors.
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