ReviewBiomedical engineering letters2022
Silicon photomultiplier signal readout and multiplexing techniques for positron emission tomography: a review.
Review in Biomedical engineering letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 57 citations in OpenAlex.
- High-resolution PET detectors with dual-ended readout using cost-effective highly multiplexed readout circuit and MPT2321 ASIC.EJNMMI physics · 2026Article
- Multi-Input Interaction Positioning and Signal Demultiplexing With Deep Learning in Semi-Monolithic Detectors.IEEE transactions on radiation and plasma medical sciences · 2026Article
- Investigating the timing behavior of compton scattering in BGO for time-of-flight PET.Physics in medicine and biology · 2026Article
- Improved Edge Pixel Resolution in Modular PET Detectors with Partly Segmented Light Guides.Sensors (Basel, Switzerland) · 2025Article
- Energy estimation methods for positron emission tomography detectors composed of multiple scintillators.Biomedical engineering letters · 2025Article
- Time to shift to Digital PET/CT?Nuclear medicine and molecular imaging · 2025Article
- Comprehensive simulation study and preliminary results on various shapes of nanopatterns for light extraction improvement in scintillation crystal.Biomedical engineering letters · 2025Article
- ASICs in PET: what we have and what we need.EJNMMI physics · 2025Review
- Recent Breakthroughs in PET-CT Multimodality Imaging: Innovations and Clinical Impact.Bioengineering (Basel, Switzerland) · 2024Review
- Strategies for mitigating inter-crystal scattering effects in positron emission tomography: a comprehensive review.Biomedical engineering letters · 2024Review
- PET Detectors Based on Multi-Resolution SiPM Arrays.IEEE transactions on radiation and plasma medical sciences · 2024Article
- Characterization of external optical crosstalk reduction for SiPM-based scintillation detectors with an optical bandpass filter.Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment · 2024Article
- A Portable Three-Layer Compton Camera for Wide-Energy-Range Gamma-ray Imaging: Design, Simulation and Preliminary Testing.Sensors (Basel, Switzerland) · 2023Article
- A Preclinical Positron Emission Tomography (PET) and Electron-Paramagnetic-Resonance-Imaging (EPRI) Hybrid System: PET Detector Module.IEEE transactions on radiation and plasma medical sciences · 2023Article
- Decision Tree-Based Demultiplexing for Prism-PET.IEEE transactions on nuclear science · 2023Article
- Organ-Specific Positron Emission Tomography Scanners for Breast Imaging: Comparison between the Performances of Prior and Novel Models.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, silicon photomultiplier (SiPM) is replacing the photomultiplier tube (PMT) in positron emission tomography (PET) systems due to its superior properties, such as fast single-photon timing response, small gap between adjacent photosensitive pixels in the array, and insensitivity to magnetic fields. One of the technical challenges when developing SiPM-based PET systems or other position-sensitive radiation detectors is the large number of output channels coming from the SiPM array. Therefore, various signal multiplexing methods have been proposed to reduce the number of output channels and the load on the subsequent data acquisition (DAQ) system. However, the large PN-junction capacitance and quenching resistance of the SiPM yield undesirable resistance-capacitance delay when multiple SiPMs are combined, which subsequently causes the accumulation of dark counts and signal fluctuation of SiPMs. Therefore, without proper SiPM signal handling and processing, the SiPMs may yield worse timing characteristics than the PMTs. This article reviews the evolution of signal readout and multiplexing methods for the SiPM. In this review, we focus primarily on analog electronics for SiPM signal multiplexing, which allows for the reduction of DAQ channels required for the SiPM-based position-sensitive detectors used in PET and other radiation detector systems. Although the applications of most technologies described in the article are not limited to PET systems, the review highlights efforts to improve the physical performance (e.g. spatial, energy, and timing resolutions) of PET detectors and systems.
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