ArticleInternational journal of biochemistry and molecular biology2022
Effect of iron deficiency anaemia over glycated hemoglobin in non-diabetic women.
Article in International journal of biochemistry and molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 4 citations in OpenAlex.
- Review
- The prevalence of anemia among type 2 diabetes mellitus with respect to renal function at a tertiary care hospital: A case-control study.Bioinformation · 2026Article
- Article
- Glycated albumin may have a complementary role to glycated hemoglobin in glucose monitoring in childhood acute leukemia.Annals of pediatric endocrinology & metabolism · 2024Article
- Is there a lack of a glucose monitoring and management protocol for preventing hyperglycemia and glucocorticoid-induced diabetes mellitus in leprosy reactions?PLoS neglected tropical diseases · 2024Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlycated hemoglobin (HbA1c) is a form of hemoglobin bound to glucose and used as an index of glycaemic control reflecting glucose levels of the previous three months. Iron deficiency anemia (IDA) is the commonest form of anemia that affects HbA1c. Reports on the effects of IDA on HbA1c levels are inconsistent in India. Therefore, the study correlated the HbA1c and IDA in non-diabetic female patients.
methodsA correlative study between HbA1c and IDA was carried out at the Department of Biochemistry, A. J. Institute of Medical Sciences, Mangaluru, India. A total of 50 non-diabetic female patients, aged between 20-50 years, with decreased levels of Hb, MCV and MCHC were selected. Their ferritin levels were determined by ELISA method to confirm IDA. Forty confirmed iron-deficient samples whose serum ferritin levels were <90 pg/dL, were tested for HbA1c levels by nephelometry method.
resultsHbA1c correlated positively with serum ferritin, Hb, MCV, MCH and MCHC (P<0.05). There was a significant decrease in mean value of HbA1c in those with severe anemia (4.50±0.34) compared to those with moderate anemia (5.18±0.35) (P<0.001).
conclusionResults showed positive correlation of HbA1c with ferritin and hemoglobin. Therefore, iron status should be considered during the interpretation of the HbA1c concentrations in diabetes mellitus.
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Identifiers
35891642PMC9301143W4288220025What OpenQuestion holds
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