Evidence map›Paper›PMID 35891535›Full record

Observational studyViruses2022

A Testing Campaign Intervention Consisting of Peer-Facilitated Engagement, Point-of-Care HCV RNA Testing, and Linkage to Nursing Support to Enhance Hepatitis C Treatment Uptake among People Who Inject Drugs: The ETHOS Engage Study.

Anna Conway, Heather Valerio, Maryam Alavi, David Silk, Carla Treloar, Behzad Hajarizadeh, Alison D Marshall, Marianne Martinello, Andrew Milat, Adrian Dunlop and 17 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

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  10. 'Canadian liver journal · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 10 institutions in 1 country.

Anna ConwayThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0002-9082-9714
Heather ValerioThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
Maryam AlaviThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
David SilkThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
Carla TreloarCentre for Social Research in Health, UNSW Sydney, Sydney, NSW 2052, Australia.
Behzad HajarizadehThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0003-2212-2028
Alison D MarshallThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
Marianne MartinelloThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
Andrew MilatCentre for Epidemiology and Evidence, NSW Health, Sydney, NSW 2065, Australia.
Adrian DunlopHepatitis NSW, Surry Hills, NSW 2010, Australia.
Carolyn MurrayPopulation Health Strategy & Performance, NSW Health, Sydney, NSW 2065, Australia.
Bianca PrainPopulation Health Strategy & Performance, NSW Health, Sydney, NSW 2065, Australia.
Charles HendersonNSW Users and AIDS Association, Surry Hills, NSW 2010, Australia.
Janaki AminDepartment of Health Systems and Populations, Macquarie University, Sydney, NSW 2109, Australia.
Phillip ReadKirketon Road Centre, Sydney, NSW 2010, Australia.
Pip MarksThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
Louisa DegenhardtNational Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW 2052, Australia.
Jeremy HayllarAlcohol and Drug Service, Metro North Mental Health, Metro North Hospital and Health Service, Brisbane, QLD 4029, Australia.
David ReidDrug and Alcohol Service, Illawarra Shoalhaven Local Health District, Wollongong, NSW 2500, Australia.
Carla GortonCairns Sexual Health Service, Cairns, QLD 4870, Australia.
Thao LamDrug Health, Western Sydney Local Health District, Sydney, NSW 2145, Australia.
Michael ChristmassNext Step Community Alcohol and Drug Service, Perth, WA 6004, Australia.
Alexandra WadeMid North Coast Liver Clinic, Mid North Coast Local Health District, Coffs Harbour, NSW 2450, Australia.
Mark MontebelloNorth Sydney Local Health District, Sydney, NSW 2077, Australia.ORCID 0000-0002-1776-3974
Gregory J DoreThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.
Jason GrebelyThe Kirby Institute, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0002-1833-2017
ETHOS Engage Study Group
UNSW Sydney · AUNew South Wales Department of Health · AUSydney Local Health District · AUAustralian Centre for HIV and Hepatitis Virology Research · AUCairns Hospital · AUCentral Coast Local Health District · AUCurtin University · AUIllawarra Shoalhaven Local Health District · AUMacquarie University · AUMetro South Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated HCV treatment initiation among people who inject drugs (PWID) following an intervention of campaign days involving peer connection, point-of-care HCV RNA testing, and linkage to nursing support. ETHOS Engage is an observational cohort study of PWID attending 25 drug treatment clinics and needle and syringe programs in Australia (May 2018-September 2019). Point-of-care results were provided to the nurse, facilitating confirmatory testing and treatment. The study aimed to evaluate treatment uptake and factors associated with treatment at 24 months post-enrolment. There were 317 people with current HCV infection and eligible for treatment (median age 43, 65% male, 15% homeless, 69% receiving opioid agonist treatment, 70% injected in last month). Overall, 15% (47/317), 27% (85/317), 38% (120/317), and 49% (155/317) of people with current HCV infection had initiated treatment at 3-, 6-, 12-, and 24-months following testing, respectively. Homelessness (adjusted hazard ratio (aHR): 0.40; 95% confidence interval: 0.23, 0.71) and incarceration in the past 12 months (vs. never, aHR:0.46; 0.28, 0.76) were associated with decreased treatment initiation in the 24 months post-enrolment. This testing campaign intervention facilitated HCV treatment uptake among PWID. Further interventions are needed to achieve HCV elimination among people experiencing homelessness or incarceration.

Indexed as

Drug UsersHepatitis CSubstance Abuse, IntravenousAdultAntiviral AgentsFemaleHepacivirusHumansMalePoint-of-Care SystemsRNAAntiviral AgentsRNAdirect-acting antiviral eraHepatitis C virus eliminationHepatitis C virus infectionHepatitis C virus treatmentpeople who inject drugs

Identifiers

PMID35891535
PMCPMC9316739
OpenAlexW4285732486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.