Evidence map›Paper›PMID 35891435›Full record

ArticleViruses2022

Comparison of the Hemagglutination Inhibition Titers against Influenza Vaccine Strains in Japan from the 2017/2018 to 2021/2022 Seasons Using a Single Set of Serum Samples.

Naruhito Otani, Kazuhiko Nakajima, Kaori Ishikawa, Kaoru Ichiki, Yoshiko Yoda, Takashi Ueda, Yoshio Takesue, Takuma Yamamoto, Susumu Tanimura, Masayuki Shima and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Naruhito OtaniDepartment of Public Health, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Kazuhiko NakajimaDepartment of Infection Control and Prevention, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Kaori IshikawaDepartment of Infection Control and Prevention, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Kaoru IchikiDepartment of Infection Control and Prevention, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Yoshiko YodaDepartment of Public Health, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Takashi UedaDepartment of Infection Control and Prevention, Hyogo Medical University, Nishinomiya 663-8501, Japan.ORCID 0000-0002-5176-9050
Yoshio TakesueDepartment of Infection Control and Prevention, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Takuma YamamotoDepartment of Legal Medicine, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Susumu TanimuraDepartment of Public Health Nursing, Mie University Graduate School of Medicine, Tsu 514-0001, Japan.ORCID 0000-0003-2897-8249
Masayuki ShimaDepartment of Public Health, Hyogo Medical University, Nishinomiya 663-8501, Japan.ORCID 0000-0002-8783-7879
Toshiomi OkunoDepartment of Microbiology, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Hyogo University · JPMie University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Japan, inactivated influenza vaccines are used. We measured titers of antibodies to vaccine strains of three influenza types-influenza A (H1N1), influenza A (H3N2), and influenza B/Victoria-from the 2017/2018 to 2021/2022 seasons, but not for influenza A (H3N2) from the 2018/2019 season, using a single set of serum samples from 34 healthy volunteers, and assessed the consistency in antibody positivity between seasons. The antibody titers in the 2017/2018 season were used as a reference. The influenza A (H1N1) antibody titer in 2019/2020 did not differ significantly from that in the 2017/2018 season, but the titers varied in the two subsequent seasons. The influenza A (H3N2) antibody titers toward the 2019/2020, 2020/2021, and 2021/2022 seasonal viruses differed significantly from that in the 2017/2018 season. The influenza B/Victoria antibody titer toward the 2019/2020 seasonal antigen differed from that in the 2017/2018 season, and the antibody positivity was inconsistent between seasons; however, the antibody titer in the 2020/2021 season did not differ significantly from those in the prior two seasons, and the antibody positivity was consistent between seasons. Antibody titers and their consistency can be used to evaluate cross-immunity of antibodies.

Indexed as

Influenza A virusInfluenza A Virus, H1N1 SubtypeInfluenza, HumanInfluenza VaccinesAntibodies, ViralHemagglutinationHemagglutination Inhibition TestsHumansInfluenza A Virus, H3N2 SubtypeInfluenza B virusJapanSeasonsVaccines, InactivatedAntibodies, ViralInfluenza VaccinesVaccines, Inactivatedcross-immunityinfluenza A (H1N1)influenza A (H3N2)influenza B/Victoria lineageserologyvaccine strain

Identifiers

PMID35891435
PMCPMC9323423
OpenAlexW4283738780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.