Evidence map›Paper›PMID 35891368›Full record

ArticleViruses2022

Experimental Infections of Pigs with African Swine Fever Virus (Genotype II); Studies in Young Animals and Pregnant Sows.

Louise Lohse, Jens Nielsen, Åse Uttenthal, Ann Sofie Olesen, Bertel Strandbygaard, Thomas Bruun Rasmussen, Graham J Belsham, Anette Bøtner

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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  5. Identification ofFrontiers in microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Louise LohseNational Veterinary Institute, Technical University of Denmark, Lindholm, DK-4771 Kalvehave, Denmark.ORCID 0000-0002-6769-5447
Jens NielsenNational Veterinary Institute, Technical University of Denmark, Lindholm, DK-4771 Kalvehave, Denmark.ORCID 0000-0002-4566-5343
Åse UttenthalNational Veterinary Institute, Technical University of Denmark, Lindholm, DK-4771 Kalvehave, Denmark.
Ann Sofie OlesenStatens Serum Institute, Artillerivej 5, DK-2300 Copenhagen S, Denmark.ORCID 0000-0002-6161-3439
Bertel StrandbygaardNational Veterinary Institute, Technical University of Denmark, Lindholm, DK-4771 Kalvehave, Denmark.
Thomas Bruun RasmussenNational Veterinary Institute, Technical University of Denmark, Lindholm, DK-4771 Kalvehave, Denmark.ORCID 0000-0002-4241-1559
Graham J BelshamNational Veterinary Institute, Technical University of Denmark, Lindholm, DK-4771 Kalvehave, Denmark.ORCID 0000-0003-1187-4873
Anette BøtnerNational Veterinary Institute, Technical University of Denmark, Lindholm, DK-4771 Kalvehave, Denmark.ORCID 0000-0002-0558-0222
Statens Serum Institut · DKTechnical University of Denmark · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever is an important viral disease of wild and domestic pigs. To gain further knowledge of the properties of the currently circulating African swine fever virus (ASFV), experimental infections of young pigs (approximately 8 weeks of age) and pregnant sows (infected at about 100 days of gestation) with the genotype II ASFV Georgia/2007 were performed. The inoculated young pigs developed typical clinical signs of the disease and the infection was transmitted (usually within 3-4 days) to all of the "in contact" animals that shared the same pen. Furthermore, typical pathogical lesions for ASFV infection were found at necropsy. Inoculation of pregnant sows with the same virus also produced rapid onset of disease from post-infection day three; two of the three sows died suddenly on post-infection day five, while the third was euthanized on the same day for animal welfare reasons. Following necropsy, the presence of ASFV DNA was detected in tonsils, spleen and lymph nodes of some of the fetuses, but the levels of viral DNA were much lower than in these tissues from the sows. Thus, only limited transplacental transmission occurred during the course of this experiment. These studies contribute towards further understanding about the spread of this important viral disease in domestic pigs.

Indexed as

African Swine FeverAfrican Swine Fever VirusAnimalsDNA, ViralFemaleGenotypePregnancySus scrofaSwineDNA, ViralAfrican swine feverdomestic pigsexperimental infectionvirus transmission

Identifiers

PMID35891368
PMCPMC9318005
OpenAlexW4283593265

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.