Evidence map›Paper›PMID 35891359›Full record

ArticleViruses2022

Description of a One-Year Succession of Variants of Interest and Concern of SARS-CoV-2 in Venezuela.

Rossana C Jaspe, Carmen L Loureiro, Yoneira Sulbaran, Zoila C Moros, Pierina D'Angelo, Mariana Hidalgo, Lieska Rodríguez, Víctor Alarcón, Marwan Aguilar, Doneyla Sánchez and 6 more

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Rossana C JaspeLaboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.ORCID 0000-0002-4816-1378
Carmen L LoureiroLaboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.
Yoneira SulbaranLaboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.ORCID 0000-0002-3170-353X
Zoila C MorosLaboratorio de Biología de Virus, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.
Pierina D'AngeloDirección de Diagnóstico y Vigilancia Epidemiológca, Instituto Nacional de Higiene "Rafael Rangel", Caracas 1053, Venezuela.
Mariana HidalgoLaboratorio de Inmunoparasitología, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.
Lieska RodríguezDirección de Diagnóstico y Vigilancia Epidemiológca, Instituto Nacional de Higiene "Rafael Rangel", Caracas 1053, Venezuela.
Víctor AlarcónDirección de Diagnóstico y Vigilancia Epidemiológca, Instituto Nacional de Higiene "Rafael Rangel", Caracas 1053, Venezuela.
Marwan AguilarDirección de Diagnóstico y Vigilancia Epidemiológca, Instituto Nacional de Higiene "Rafael Rangel", Caracas 1053, Venezuela.
Doneyla SánchezDirección de Diagnóstico y Vigilancia Epidemiológca, Instituto Nacional de Higiene "Rafael Rangel", Caracas 1053, Venezuela.
Jesús RamírezDirección de Diagnóstico y Vigilancia Epidemiológca, Instituto Nacional de Higiene "Rafael Rangel", Caracas 1053, Venezuela.
Domingo J GarzaroLaboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.ORCID 0000-0002-9956-5786
José Luis ZambranoLaboratorio de Biología de Virus, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.
Ferdinando LiprandiLaboratorio de Biología de Virus, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.ORCID 0000-0001-8084-8252
Héctor R RangelLaboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.ORCID 0000-0001-5937-9690
Flor H PujolLaboratorio de Virología Molecular, Centro de Microbiología y Biología Celular, Instituto Venezolano de Investigaciones Científicas, Caracas 1020, Venezuela.ORCID 0000-0001-6086-6883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some of the lineages of SARS-CoV-2, the new coronavirus responsible for COVID-19, exhibit higher transmissibility or partial resistance to antibody-mediated neutralization and were designated by WHO as Variants of Interests (VOIs) or Concern (VOCs). The aim of this study was to monitor the dissemination of VOIs and VOCs in Venezuela from March 2021 to February 2022. A 614 nt genomic fragment was sequenced for the detection of some relevant mutations of these variants. Their presence was confirmed by complete genome sequencing, with a correlation higher than 99% between both methodologies. After the introduction of the Gamma VOC since the beginning of the year 2021, the variants Alpha VOC and Lambda VOI were detected as early as March 2021, at a very low frequency. In contrast, the Mu VOI, detected in May 2021, was able to circulate throughout the country. After the detection of the Delta VOC in June 2021, it became the predominant circulating variant. With the arrival of the Omicron VOC in December, this variant was able to displace the Delta one in less than one month.

Indexed as

COVID-19SARS-CoV-2Base SequenceHumansMutationSpike Glycoprotein, CoronavirusVenezuelaSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19mutationsrapid screeningSARS-CoV-2Variants of Concern

Identifiers

PMID35891359
PMCPMC9317613

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.