Evidence map›Paper›PMID 35891340›Full record

ArticleViruses2022

Development and Validation of Indirect Enzyme-Linked Immunosorbent Assays for Detecting Antibodies to SARS-CoV-2 in Cattle, Swine, and Chicken.

Abhinay Gontu, Erika A Marlin, Santhamani Ramasamy, Sabarinath Neerukonda, Gayatri Anil, Jasmine Morgan, Meysoon Quraishi, Chen Chen, Veda Sheersh Boorla, Ruth H Nissly and 19 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Little Brown Bats (Viruses · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 4 institutions in 2 countries.

Abhinay GontuDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0001-6260-7092
Erika A MarlinDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Santhamani RamasamyDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Sabarinath NeerukondaU.S. Department of Health and Human Services, Silver Spring, MD 20993, USA.
Gayatri AnilDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Jasmine MorganDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Meysoon QuraishiDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Chen ChenDepartment of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-8316-7898
Veda Sheersh BoorlaDepartment of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
Ruth H NisslyAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-3102-7447
Padmaja JakkaDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Shubhada K ChotheDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-7109-7810
Abirami RavichandranDepartment of Integrative and Biomedical Physiology, The Pennsylvania State University, University Park, PA 16802, USA.
Nishitha KodaliDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Saranya AmirthalingamDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Lindsey LaBellaDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-2948-6166
Kathleen KellyAnimal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Pazhanivel NatesanMadras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai 600007, India.
Allen M MinnsHuck Institute of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Randall M RossiHuck Institute of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Jacob R WernerDepartment of Animal Science, The Pennsylvania State University, University Park, PA 16802, USA.
Ernest HovinghDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-1013-0282
Scott E LindnerHuck Institute of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Deepanker TewariPennsylvania Department of Agriculture, Pennsylvania Veterinary Laboratory, Harrisburg, PA 17110, USA.
Vivek KapurHuck Institute of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.
Kurt J VandegriftHuck Institute of Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-5690-3300
Costas D MaranasDepartment of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-1508-1398
Meera Surendran NairDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-4686-8414
Suresh V KuchipudiDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-8640-254X
Pennsylvania State University · USPennsylvania Department of Agriculture · USTamil Nadu Veterinary and Animal Sciences University · INUnited States Department of Health and Human Services · US

Funding

Carbon nanotube integrated microdevice for next generation sequencing based virus discoveryR01AI134911 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI ZHENG, SIYANG · 2018 to 2022
$2.0M
Infection and prevalence of a new segmented flavivirus in the United StatesR21AI156406 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KAPOOR, AMIT · 2021 to 2022
$440k
NIH HHS 1R01AI134911NIH HHS 1R21AI156406-01
6 · The paper itself

Abstract

Multiple domestic and wild animal species are susceptible to SARS-CoV-2 infection. Cattle and swine are susceptible to experimental SARS-CoV-2 infection. The unchecked transmission of SARS-CoV-2 in animal hosts could lead to virus adaptation and the emergence of novel variants. In addition, the spillover and subsequent adaptation of SARS-CoV-2 in livestock could significantly impact food security as well as animal and public health. Therefore, it is essential to monitor livestock species for SARS-CoV-2 spillover. We developed and optimized species-specific indirect ELISAs (iELISAs) to detect anti-SARS-CoV-2 antibodies in cattle, swine, and chickens using the spike protein receptor-binding domain (RBD) antigen. Serum samples collected prior to the COVID-19 pandemic were used to determine the cut-off threshold. RBD hyperimmunized sera from cattle (

Indexed as

COVID-19SARS-CoV-2AnimalsAntibodies, ViralCattleChickensEnzyme-Linked Immunosorbent AssayHumansPandemicsSpike Glycoprotein, CoronavirusSwineAntibodies, ViralSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2cattlechickenELISASARS-CoV-2serologysurveillanceswine

Identifiers

PMID35891340
PMCPMC9317974
OpenAlexW4283370751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.