Evidence map›Paper›PMID 35891178›Full record

ArticleVaccines2022

Safety and Immunogenicity of Inactivated

Johnny Chun-Chau Sung, Nelson Cheuk-Yin Lai, Kam-Chau Wu, Man-Chung Choi, Chloe Ho-Yi Ma, Jayman Lin, Cheong-Nang Kuok, Wai-Leng Leong, Weng-Kei Lam, Yusuf Khwaja Hamied and 3 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Chemical Inactivation ofMicroorganisms · 2025
    Article
  4. Article
  5. Article
  6. Frontiers in immunology · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Journal of fungi (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Johnny Chun-Chau SungResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Nelson Cheuk-Yin LaiResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Kam-Chau WuResearch Department, DreamTec Cytokines Limited, Hong Kong, China.ORCID 0000-0003-1679-7483
Man-Chung ChoiResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Chloe Ho-Yi MaResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Jayman LinResearch Department, DreamTec Cytokines Limited, Hong Kong, China.
Cheong-Nang KuokMacao Greater Bay Area Association of Healthcare Providers, Macau 999078, China.
Wai-Leng LeongMacao Greater Bay Area Association of Healthcare Providers, Macau 999078, China.
Weng-Kei LamMacao Greater Bay Area Association of Healthcare Providers, Macau 999078, China.
Yusuf Khwaja HamiedCipla Limited, Mumbai 400013, India.
Dominic Man-Kit LamL&L Immunotherapy Company Limited, Hong Kong, China.
Eric Tung-Po SzeSchool of Science and Technology, Hong Kong Metropolitan University, Hong Kong, China.ORCID 0000-0001-6197-0893
Keith Wai-Yeung KwongResearch Department, DreamTec Cytokines Limited, Hong Kong, China.ORCID 0000-0001-5229-0124
Cipla (India) · INSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus diseases 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have threatened the world for more than 2 years. Multiple vaccine candidates have been developed and approved for emergency use by specific markets, but multiple doses are required to maintain the antibody level. Preliminary safety and immunogenicity data about an oral dose vaccine candidate using recombinant

Indexed as

Bacillus subtilisCOVID-19oral vaccineSARS-CoV-2spike proteinsporulation

Identifiers

PMID35891178
PMCPMC9322707
OpenAlexW4283574641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.