Evidence map›Paper›PMID 35891166›Full record

ArticleVaccines2022

Immunization and SARS-CoV-2 Antibody Seroprevalence in a Country with High Vaccination Coverage: Lessons from Chile.

Ximena Aguilera, Claudia González, Mauricio Apablaza, Paola Rubilar, Gloria Icaza, Muriel Ramírez-Santana, Claudia Pérez, Lina Jimena Cortes, Loreto Núñez-Franz, Rubén Quezada-Gaete and 6 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Ximena AguileraCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, San Carlos de Apoquindo, Las Condes, Santiago 7610658, Chile.ORCID 0000-0002-8153-6733
Claudia GonzálezCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, San Carlos de Apoquindo, Las Condes, Santiago 7610658, Chile.
Mauricio ApablazaFacultad de Gobierno, Universidad del Desarrollo, San Carlos de Apoquindo, Las Condes, Santiago 7610658, Chile.
Paola RubilarCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, San Carlos de Apoquindo, Las Condes, Santiago 7610658, Chile.ORCID 0000-0003-3578-459X
Gloria IcazaInstituto de Matemáticas, Universidad de Talca, Talca 3460000, Chile.
Muriel Ramírez-SantanaPublic Health Department, Faculty of Medicine, Universidad Católica del Norte, Coquimbo 1780000, Chile.ORCID 0000-0002-3642-6965
Claudia PérezEscuela de Enfermería, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0003-2870-5662
Lina Jimena CortesInstituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.
Loreto Núñez-FranzDepartamento de Salud Pública, Facultad de Ciencias de la Salud, Universidad de Talca, Avenida Uno Poniente #1141, Talca 3460000, Chile.
Rubén Quezada-GaetePublic Health Department, Faculty of Medicine, Universidad Católica del Norte, Coquimbo 1780000, Chile.
Carla Castillo-LabordeCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, San Carlos de Apoquindo, Las Condes, Santiago 7610658, Chile.
Juan CorreaCentro Producción del Espacio, Universidad de las Américas, Santiago 7500975, Chile.ORCID 0000-0002-0612-8780
Macarena SaidDepartamento de Salud Pública, Facultad de Ciencias de la Salud, Universidad de Talca, Avenida Uno Poniente #1141, Talca 3460000, Chile.
Juan HormazábalInstituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0003-0726-2778
Cecilia VialInstituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.ORCID 0000-0002-0399-6144
Pablo VialInstituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago 7610658, Chile.
Universidad del Desarrollo · CLUniversity of Talca · CLUniversidad Católica del Norte · CLUniversity of the Americas · CL

Funding

World Health Organization WHO Unity Studies COVID-19 Solidarity Response Fund and the German Federal Ministry of health (BMG) Research and Development Fund
6 · The paper itself

Abstract

Chile is among the most successful nations worldwide in terms of its COVID-19 vaccine rollout. By 31 December 2021, 84.1% of the population was fully vaccinated, and 56.1% received booster doses using different COVID-19 vaccines. In this context, we aimed to estimate the prevalence of anti-SARS-CoV-2 antibodies following the infection and vaccination campaign. Using a three-stage stratified sampling, we performed a population-based cross-sectional serosurvey based on a representative sample of three Chilean cities. Selected participants were blood-sampled on-site and answered a short COVID-19 and vaccination history questionnaire using Wantai SARS-CoV-2 Ab ELISA to determine seroprevalence. We recruited 2198 individuals aged 7-93 between 5 October and 25 November 2021; 2132 individuals received COVID-19 vaccinations (97%), 67 (3.1%) received one dose, 2065 (93.9%) received two doses, and 936 received the booster jab (42.6%). Antibody seroprevalence reached 97.3%, ranging from 40.9% among those not vaccinated to 99.8% in those with booster doses (OR = 674.6, 154.8-2938.5). SARS-CoV-2 antibodies were associated with vaccination, previous COVID-19 diagnosis, age group, and city of residence. In contrast, we found no significant differences in the type of vaccine used, education, nationality, or type of health insurance. We found a seroprevalence close to 100%, primarily due to the successful vaccination program, which strongly emphasizes universal access.

Indexed as

AZD1222BNT162b2COVID-19cross-sectionalELISASinovac Coronavacvaccines

Identifiers

PMID35891166
PMCPMC9322351
OpenAlexW4283386177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.