Evidence map›Paper›PMID 35891052›Full record

ArticleSensors (Basel, Switzerland)2022

Tunable White Light for Elders (TWLITE): A Protocol Demonstrating Feasibility and Acceptability for Deployment, Remote Data Collection, and Analysis of a Home-Based Lighting Intervention in Older Adults.

Jonathan E Elliott, Carolyn E Tinsley, Christina Reynolds, Randall J Olson, Kristianna B Weymann, Wan-Tai M Au-Yeung, Andrea Wilkerson, Jeffrey A Kaye, Miranda M Lim

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jonathan E ElliottVA Portland Health Care System, Research Service, Portland, OR 97239, USA.ORCID 0000-0002-6992-6851
Carolyn E TinsleyVA Portland Health Care System, Research Service, Portland, OR 97239, USA.
Christina ReynoldsDepartment of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.
Randall J OlsonVA Portland Health Care System, Research Service, Portland, OR 97239, USA.
Kristianna B WeymannSchool of Nursing, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0002-6421-5874
Wan-Tai M Au-YeungDepartment of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.
Andrea WilkersonPacific Northwest National Laboratory, Portland, OR 97239, USA.ORCID 0000-0003-3586-2105
Jeffrey A KayeDepartment of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.
Miranda M LimDepartment of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0003-3876-3196
Oregon Health & Science University · USPacific Northwest National Laboratory · USVA Portland Health Care System · US

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Zachary Beattie · 2020 to 2026
$28.6M
Pilot CoreP30AG024978 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KAYE, JEFFREY A · 2004 to 2023
$9.0M
Agitation in Alzheimer's Disease: Identification and Prediction Using Digital Behavioral Markers and Indoor Environmental FactorsK25AG071841 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI AU-YEUNG, WAN-TAI · 2021 to 2025
$731k
A Sleep Intervention to Improve Rehabilitation in Veterans with Chronic mTBIIK2RX002947 · VA · PORTLAND VA MEDICAL CENTER · PI ELLIOTT, JONATHAN E · 2019 to 2025
–
CSRD VA I01 CX002022NIA NIH HHS K25 AG071841NIA NIH HHS P30 AG024978NIA NIH HHS P30 AG066518RRD VA IK2 RX002947
6 · The paper itself

Abstract

Sleep disturbances are common in older adults and may contribute to disease progression in certain populations (e.g., Alzheimer's disease). Light therapy is a simple and cost-effective intervention to improve sleep. Primary barriers to light therapy are: (1) poor acceptability of the use of devices, and (2) inflexibility of current devices to deliver beyond a fixed light spectrum and throughout the entirety of the day. However, dynamic, tunable lighting integrated into the native home lighting system can potentially overcome these limitations. Herein, we describe our protocol to implement a whole-home tunable lighting system installed throughout the homes of healthy older adults already enrolled in an existing study with embedded home assessment platforms (Oregon Center for Aging & Technology-ORCATECH). Within ORCATECH, continuous data on room location, activity, sleep, and general health parameters are collected at a minute-to-minute resolution over years of participation. This single-arm longitudinal protocol collected participants' light usage in addition to ORCATECH outcome measures over a several month period before and after light installation. The protocol was implemented with four subjects living in three ORCATECH homes. Technical/usability challenges and feasibility/acceptability outcomes were explored. The successful implementation of our protocol supports the feasibility of implementing and integrating tunable whole-home lighting systems into an automated home-based assessment platform for continuous data collection of outcome variables, including long-term sleep measures. Challenges and iterative approaches are discussed. This protocol will inform the implementation of future clinical intervention trials using light therapy in patients at risk for developing Alzheimer's disease and related conditions.

Indexed as

Alzheimer DiseaseSleep Wake DisordersAgedData CollectionFeasibility StudiesHumansLightingAlzheimer’sprotocolsleepsmart living applicationstunable light

Identifiers

PMID35891052
PMCPMC9320387
OpenAlexW4285796498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.