Evidence map›Paper›PMID 35890665›Full record

ReviewPolymers2022

A Review of PRESAGE Radiochromic Polymer and the Compositions for Application in Radiotherapy Dosimetry.

Muhammad Zamir Mohyedin, Hafiz Mohd Zin, Mohd Zulfadli Adenan, Ahmad Taufek Abdul Rahman

Open access · goldAbstract readReview
In one paragraph

Review in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Advancements in Tissue-Equivalent Gel Dosimeters.Gels (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Gel Dosimetry.Gels (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Muhammad Zamir MohyedinSchool of Physics and Material Studies, Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam 40450, Selangor, Malaysia.
Hafiz Mohd ZinAdvanced Medical & Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas 13700, Penang, Malaysia.ORCID 0000-0002-5679-7210
Mohd Zulfadli AdenanCentre of Medical Imaging, Faculty of Health Sciences, Universiti Teknologi MARA, Cawangan Selangor Campus of Puncak Alam, Puncak Alam 42300, Selangor, Malaysia.
Ahmad Taufek Abdul RahmanSchool of Physics and Material Studies, Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam 40450, Selangor, Malaysia.ORCID 0000-0001-6476-6900
Universiti Teknologi MARA · MYUniversiti Sains Malaysia · MY

Funding

Ministry of Higher Education 600-IRMI/FRGS 5/3 (412/2019)
6 · The paper itself

Abstract

Recent advances in radiotherapy technology and techniques have allowed a highly conformal radiation to be delivered to the tumour target inside the body for cancer treatment. A three-dimensional (3D) dosimetry system is required to verify the accuracy of the complex treatment delivery. A 3D dosimeter based on the radiochromic response of a polymer towards ionising radiation has been introduced as the PRESAGE dosimeter. The polyurethane dosimeter matrix is combined with a leuco-dye and a free radical initiator, whose colour changes in proportion to the radiation dose. In the previous decade, PRESAGE gained improvement and enhancement as a 3D dosimeter. Notably, PRESAGE overcomes the limitations of its predecessors, the Fricke gel and the polymer gel dosimeters, which are challenging to fabricate and read out, sensitive to oxygen, and sensitive to diffusion. This article aims to review the characteristics of the radiochromic dosimeter and its clinical applications. The formulation of PRESAGE shows a delicate balance between the number of radical initiators, metal compounds, and catalysts to achieve stability, optimal sensitivity, and water equivalency. The applications of PRESAGE in advanced radiotherapy treatment verifications are also discussed.

Indexed as

polymer dosimeterPRESAGEradiation dosimeterradiotherapythree-dimensional dosimetry

Identifiers

PMID35890665
PMCPMC9320230
OpenAlexW4285732814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.