Evidence map›Paper›PMID 35890228›Full record

ArticlePharmaceutics2022

Combination of Six Individual Derivatives of the Pom-1 Antibiofilm Peptide Doubles Their Efficacy against Invasive and Multi-Resistant Clinical Isolates of the Pathogenic Yeast Candida albicans

Michelle Häring, Valerie Amann, Ann-Kathrin Kissmann, Tilmann Herberger, Christopher Synatschke, Nicole Kirsch-Pietz, Julio A Perez-Erviti, Anselmo J Otero-Gonzalez, Fidel Morales-Vicente, Jakob Andersson and 5 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Antifungal therapy ofBiofilm · 2023
    Article
  11. Cm-p5 Peptide Dimers Inhibit Biofilms ofInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Michelle HäringInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Valerie AmannInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Ann-Kathrin KissmannInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Tilmann HerbergerMax Planck Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.
Christopher SynatschkeMax Planck Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.ORCID 0000-0002-4259-6696
Nicole Kirsch-PietzMax Planck Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.
Julio A Perez-ErvitiCenter for Protein Studies, Faculty of Biology, University of Havana, 25 Street, Havana 10400, Cuba.
Anselmo J Otero-GonzalezCenter for Protein Studies, Faculty of Biology, University of Havana, 25 Street, Havana 10400, Cuba.ORCID 0000-0002-1719-0117
Fidel Morales-VicenteSynthetic Peptides Group, Center for Genetic Engineering and Biotechnology, Havana 10600, Cuba.
Jakob AnderssonAIT Austrian Institute of Technology GmbH, Giefinggasse 4, 1210 Vienna, Austria.
Tanja WeilMax Planck Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.
Steffen StengerInstitute for Medical Microbiology and Hygiene, University Hospital Ulm, 89081 Ulm, Germany.
Armando RodríguezCore Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0001-5921-3770
Ludger StändkerCore Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Frank RosenauInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID 0000-0002-9297-6419

Funding

Alexander von Humboldt Foundation Research Group Linkage Program (No. 1160914)Baden-Württemberg Stiftung Nano-Mem-to-Tech, BiofMO_005Deutsche Forschungsgemeinschaft 465229237Deutsche Forschungsgemeinschaft CRC1279European Union Horizon 2020 686271 "ad-gutFederal Ministry of Education and Research BMBF-WTZ-DLR, GermanyCuba, 2018-2020 and BMBF/DLR 01DN18009)German Academic Exchange Service project-ID 57592717Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg 7533-10-5-186A and 7533-10-5-190
6 · The paper itself

Abstract

In previous studies, derivatives of the peptide Pom-1, which was originally extracted from the freshwater mollusk

Indexed as

antimicrobial peptidescombination therapyinvasive clinical isolates

Identifiers

PMID35890228
PMCPMC9319270

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.