Evidence map›Paper›PMID 35890113›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Synthesis, Structure−Activity Relationships, and Parasitological Profiling of Brussonol Derivatives as New Plasmodium falciparum Inhibitors

Camila S Barbosa, Anees Ahmad, Sarah El Chamy Maluf, Igor M R Moura, Guilherme E Souza, Giovanna A H Guerra, Roberto R Moraes Barros, Marcos L Gazarini, Anna C C Aguiar, Antonio C B Burtoloso and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Antiplasmodial Compounds fromInternational journal of molecular sciences · 2026
    Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Camila S BarbosaSão Carlos Institute of Physics, University of São Paulo, Av. João Dagnone, 1100, Santa Angelina, São Carlos 13563-120, Brazil.ORCID 0000-0001-9631-3172
Anees AhmadSão Carlos Institute of Chemistry, University of São Paulo, Av. João Dagnone, 1100, Santa Angelina, São Carlos 13563-120, Brazil.
Sarah El Chamy MalufSão Carlos Institute of Physics, University of São Paulo, Av. João Dagnone, 1100, Santa Angelina, São Carlos 13563-120, Brazil.
Igor M R MouraSão Carlos Institute of Physics, University of São Paulo, Av. João Dagnone, 1100, Santa Angelina, São Carlos 13563-120, Brazil.ORCID 0000-0003-3279-6894
Guilherme E SouzaSão Carlos Institute of Physics, University of São Paulo, Av. João Dagnone, 1100, Santa Angelina, São Carlos 13563-120, Brazil.ORCID 0000-0003-3278-6688
Giovanna A H GuerraDepartment of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04023-062, Brazil.
Roberto R Moraes BarrosDepartment of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo 04023-062, Brazil.
Marcos L GazariniDepartment of Biosciences, Federal University of São Paulo, Rua Silva Jardim, 136, Santos 11015-020, Brazil.ORCID 0000-0002-3882-6831
Anna C C AguiarSão Carlos Institute of Physics, University of São Paulo, Av. João Dagnone, 1100, Santa Angelina, São Carlos 13563-120, Brazil.
Antonio C B BurtolosoSão Carlos Institute of Chemistry, University of São Paulo, Av. João Dagnone, 1100, Santa Angelina, São Carlos 13563-120, Brazil.ORCID 0000-0003-2203-1556
Rafael V C GuidoSão Carlos Institute of Physics, University of São Paulo, Av. João Dagnone, 1100, Santa Angelina, São Carlos 13563-120, Brazil.
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance Code 001, 88887.369957/2019-00São Paulo Research Foundation 2013/07600-3, 2020/12904-5, 2013/18009-4, 2019/19708-0, 2018/06219-8, 2015/20084-0, 2018/07287-7, 2021/14319-5, 2021/03977-1, 2020/14429-2São Paulo Research Foundation 2019/17721-9
6 · The paper itself

Abstract

Malaria is a parasitic disease caused by protozoan parasites from the genus

Indexed as

antimalarialsicetexane diterpenoidsmalariaPlasmodium falciparumresistance

Identifiers

PMID35890113
PMCPMC9321043
OpenAlexW4283753780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.