Evidence map›Paper›PMID 35890108›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Linearolactone Induces Necrotic-like Death in

Raúl Argüello-García, Fernando Calzada, Bibiana Chávez-Munguía, Audifás-Salvador Matus-Meza, Elihú Bautista, Elizabeth Barbosa, Claudia Velazquez, Marta Elena Hernández-Caballero, Rosa Maria Ordoñez-Razo, José Antonio Velázquez-Domínguez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Antiprotozoal Potential of CultivatedInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Raúl Argüello-GarcíaDepartamento de Genética y Biología Molecular, Centro de Investigación y Estudios Avanzados, IPN, Mexico City 07360, Mexico.
Fernando CalzadaUnidad de Investigación Médica en Farmacología, 2° Piso CORCE, UMAE Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Av. Cuauhtémoc 330, Colonia Doctores, Mexico City 06720, Mexico.ORCID 0000-0003-1851-5988
Bibiana Chávez-MunguíaDepartamento de Infectómica y Patogénesis Molecular, CINVESTAV-IPN, Av. Instituto Politécnico Nacional No. 2508, Colonia San Pedro Zacatenco, Mexico City 07360, Mexico.
Audifás-Salvador Matus-MezaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, 985830 Nebraska Medical Center, Omaha, NE 68198, USA.
Elihú BautistaCONACyT-División de Biología Molecular, Instituto Potosino de Investigación Científica y Tecnológica A. C., San Luis Potosí 78216, Mexico.ORCID 0000-0002-7050-9182
Elizabeth BarbosaSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Salvador Díaz Mirón Esq. Plan de San Luis S/N, Miguel Hidalgo, Casco de Santo Tomas, Mexico City 11340, Mexico.ORCID 0000-0002-7111-7922
Claudia VelazquezÁrea Académica de Farmacia, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Km 4.5, Carretera Pachuca-Tulancingo, Unidad Universitaria, Pachuca 42076, Mexico.
Marta Elena Hernández-CaballeroFacultad de Medicina, Biomedicina, Benemérita Universidad Autónoma de Puebla, Puebla 72410, Mexico.ORCID 0000-0003-4174-2118
Rosa Maria Ordoñez-RazoUnidad de Investigación Médica en Genética Humana, UMAE Hospital de Pediatría 2° Piso, Centro Méddico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Av. Cuauhtémoc 330, Colonia Doctores, Mexico City 06725, Mexico.ORCID 0000-0003-4949-9175
José Antonio Velázquez-DomínguezEscuela Nacional de Medicina y Homeopatía IPN, Av. Guillermo Massieu Helguera, No. 239, La Escalera, Mexico City 07320, Mexico.ORCID 0000-0003-4504-8166
Instituto Politécnico Nacional · MXBenemérita Universidad Autónoma de Puebla · MXCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXCentro Medico Nacional Siglo XXI · MXInstitute for Scientific and Technological Research · MXMexican Social Security Institute · MXNebraska Medical Center · USUniversidad Autónoma del Estado de Hidalgo · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linearolactone (LL) is a

Indexed as

aldose reductasedocking analysisGiardia intestinalisneo-clerodane diterpenesROS productionultrastructural alterations

Identifiers

PMID35890108
PMCPMC9324340
OpenAlexW4283736348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.