Evidence map›Paper›PMID 35890068›Full record

ReviewPharmaceuticals (Basel, Switzerland)2022

Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications.

Danyang Li, Meng Liu, Wenyao Li, Qiang Fu, Liyang Wang, Enping Lai, Weixin Zhao, Kaile Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Danyang LiThe Department of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China.
Meng LiuThe Department of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China.
Wenyao LiSchool of Materials Engineering, Shanghai University of Engineering Science, Shanghai 201620, China.ORCID 0000-0003-3634-2021
Qiang FuThe Department of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China.
Liyang WangSchool of Materials Engineering, Shanghai University of Engineering Science, Shanghai 201620, China.
Enping LaiGuangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545026, China.
Weixin ZhaoWake Forest Institute of Regenerative Medicine, Winston Salem, NC 27101, USA.
Kaile ZhangThe Department of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China.

Funding

National Natural Science Foundation of China 82170694, 81700590Shanghai Jiao Tong University YG2022ZD020, YG2017QN15
6 · The paper itself

Abstract

In recent years, Prussian blue nanoparticles (PBNPs), also named Prussian blue nano-enzymes, have been shown to demonstrate excellent multi-enzyme simulation activity and anti-inflammatory properties, and can be used as reactive oxygen scavengers. Their good biocompatibility and biodegradability mean that they are ideal candidates for in vivo use. PBNPs are highly efficient electron transporters with oxidation and reduction activities. PBNPs also show considerable promise as nano-drug carriers and biological detection sensors owing to their huge specific surface area, good chemical characteristics, and changeable qualities, which might considerably increase the therapeutic impact. More crucially, PBNPs, as therapeutic and diagnostic agents, have made significant advances in biological nanomedicine. This review begins with a brief description of the synthesis methods of PBNPs, then focuses on the applications of PBNPs in tissue regeneration and inflammation according to the different properties of PBNPs. This article will provide a timely reference for further study of PBNPs as therapeutic agents.

Indexed as

anti-inflammatory effectsdrug carriernano-enzymePrussian blue nanoparticlestissue repair

Identifiers

PMID35890068
PMCPMC9323998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.